Monoethyl Phthalate (MEP) is a metabolite of plasticizer diethyl phthalate (DEP). Monoethyl Phthalate is a one of the most abundant phthalate metabolites present in human urine. It is also present in other body fluids including breast milk, serum, semen, saliva and amniotic. Monoethyl Phthalate (MEP), together with mono-benzyl phthalate and mono-isobutyl phthalate has been associated with obesity in children, anomalities in pubertal development in girls, and increased risk of endometriosis in women. MEP and MiBP (mono-isobutyl phthalate) representing low molecular weight phthalates, and MECPP (Mono-(2-ethyl-5-carboxypentyl) phthalate) and MCiOP (Mono-(carboxyisooctyl) phthalate) representing high molecular weight phthalates have been used as indicators of phthalate exposure.
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Environmental health perspectives, 125(9), 097008-097008 (2017-09-25)
Early-life phthalate exposure may influence child adiposity, but prior studies have not determined if there are periods of enhanced vulnerability to phthalates. To examine the relationship between child adiposity at 8 y of age and repeated urinary biomarkers of phthalate
Phthalates and bisphenol A (BPA) are used in some personal care products (PCPs) and containers for food processing and packaging. The Plastics and Personal-Care Product use in Pregnancy (P4) Study (2009-10) explored the association between PCP use during pregnancy and
Phthalates (diesters of phthalic acid) are widely used as plasticizers and additives in many consumer products. Laboratory animal studies have reported the endocrine-disrupting and reproductive effects of phthalates, and human exposure to this class of chemicals is a concern. Several
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