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D0806

Sigma-Aldrich

Diethylamine

BioXtra

Synonym(s):

N,N-Diethylamine, N-ethyl-ethanamine, DEA, Diethamine, Diethyl amine

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About This Item

Linear Formula:
(C2H5)2NH
CAS Number:
109-89-7
Molecular Weight:
73.14
Beilstein/REAXYS Number:
605268
EC Number:
203-716-3
MDL number:
MFCD00009032
UNSPSC Code:
12352100
PubChem Substance ID:
24893300
NACRES:
NA.21

grade

BioPerformance Certified

Quality Level

100

vapor density

2.5 (vs air)

vapor pressure

14.14 psi ( 55 °C)
180 mmHg ( 20 °C)
3.51 psi ( 20 °C)

product line

BioXtra

assay

≥97.5% (GC)

form

liquid

autoignition temp.

594 °F

expl. lim.

10.1 %

impurities

<0.0005% Phosphorus (P)

ign. residue

<0.1%

refractive index

n20/D 1.385 (lit.)

bp

55 °C (lit.)

mp

−50 °C (lit.)

solubility

H2O: 1 M at 20 °C, clear, colorless

density

0.707 g/mL at 25 °C (lit.)

anion traces

chloride (Cl-): <0.05%
sulfate (SO42-): <0.05%

cation traces

Al: <0.0005%
Ca: <0.0005%
Cu: <0.0005%
Fe: <0.0005%
K: <0.005%
Mg: <0.0005%
NH4+: <0.05%
Na: <0.005%
Pb: <0.001%
Zn: <0.0005%

functional group

amine

SMILES string

CCNCC

InChI

1S/C4H11N/c1-3-5-4-2/h5H,3-4H2,1-2H3

InChI key

HPNMFZURTQLUMO-UHFFFAOYSA-N

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General description

Diethylamine (DEA) is an organic base[1] and a weak σ-donor ligand.[2] It plays the role of a bond-breaking agent in a novel ELISA (enzyme-linked immunosorbent assay technique for measuring the avidity index (AI) of IgG-anti-PT (Immunoglobulin G-anti-pertussis toxin) antibodies.[3]

Application

Diethylamine has been used to prepare a high-pH elution solution in combination with sodium deoxycholate, which was employed during the immunoabsorption of postsynaptic density (PSD) proteins.[4]

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Oral - Acute Tox. 4 Inhalation - Eye Dam. 1 - Flam. Liq. 2 - Skin Corr. 1A - STOT SE 3

target_organs

Respiratory system

Storage Class

3 - Flammable liquids

wgk_germany

WGK 1

flash_point_f

-14.8 °F - closed cup

flash_point_c

-26 °C - closed cup

ppe

Faceshields, Gloves, Goggles

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Certificates of Analysis (COA)

Lot/Batch Number
MKCM4385
MKCL8897
SHBK8347
SHBH8836
SHBG5216V

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Alex-Mikael Barkoff et al.
Vaccine, 30(48), 6897-6902 (2012-09-18)
Pertussis toxin (PT) is a specific virulence factor of Bordetella pertussis and it is included in all acellular pertussis vaccines (aP). Although immunity after infection seems to persist longer than that after vaccination, the exact mechanism(s) is not known. Primary
Inhibited Catalyst Activation in (N-Heterocyclic carbene) PdCl2 (diethylamine) Complexes by Intramolecular Hydrogen Bonding.
Chen MT, et al.
Organometallics, 30(24), 6770-6773 (2011)
A practical and highly efficient protocol for multicomponent synthesis of β-phosphonomalononitriles and 2-amino-4H-chromen-4-yl phosphonates using diethylamine as a novel organocatalyst.
Kulkarni MA, et al.
Comptes Rendus Chimie, 15(9), 745-752 (2012)
Yen Yun-Hong et al.
Molecular & cellular proteomics : MCP, 10(10), M110-M110 (2011-07-01)
Postsynaptic density (PSD) is a protein supramolecule lying underneath the postsynaptic membrane of excitatory synapses and has been implicated to play important roles in synaptic structure and function in mammalian central nervous system. Here, PSDs were isolated from two distinct
Wen-Hsien Tsai et al.
Journal of chromatography. A, 1217(3), 250-255 (2009-12-05)
A salting-out assisted liquid extraction coupled with back-extraction by a water/acetonitrile/dichloromethane ternary component system combined with high-performance liquid chromatography with diode-array detection (HPLC-DAD) was developed for the extraction and determination of sulfonamides in solid tissue samples. After the homogenization of
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