94673

4-(Dimethylamino)pyridine

pharmaceutical impurity standard

• Synonym(s): Valaciclovir Related Compound G (USP), Valaciclovir impurity G (PhEur), N,N-Dimethylpyridin-4-amine, DMAP
• Empirical Formula (Hill Notation): C₇H₁₀N₂
• CAS Number: 1122-58-3
• Molecular Weight: 122.17
• Beilstein/REAXYS Number: 110354
• EC Number: 214-353-5
• MDL number: MFCD00006418
• UNSPSC Code: 41116107
• PubChem Substance ID: 329770372

Properties

• grade: analytical standard
• assay: ≥90.0% (TLC)
• shelf life: limited shelf life, expiry date on the label
• technique(s): HPLC: suitable; gas chromatography (GC): suitable
• impurities: ≤10% related substanced TLC impurities; ≤5% residual solvents (NMR); <5.0 wt. % water
• mp: 108-110 °C (lit.)
• solubility: 76 g/L at 20 °C
• application(s): forensics and toxicology; pharmaceutical (small molecule)
• format: neat
• SMILES string: CN(C)c1ccncc1
• InChI: 1S/C7H10N2/c1-9(2)7-3-5-8-6-4-7/h3-6H,1-2H3
• Inchi Key: VHYFNPMBLIVWCW-UHFFFAOYSA-N

Description

General description

4-(Dimethylamino)pyridine (DMAP) is an excellent catalyst for acylation of hindered alcohols and in chemical transformations. It is highly nucleophilic in nature.[1]

Application

A highly efficient catalyst for acylation reactions

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Safety Information

• pictograms: GHS06,GHS08,GHS05,GHS09
• signalword: Danger
• hcodes: H301 + H331,H310,H315,H318,H370,H411
• pcodes: P262 - P273 - P280 - P301 + P310 - P302 + P352 + P310 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 2 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Irrit. 2 - STOT SE 1
• target_organs: Nervous system
• Storage Class: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• wgk_germany: WGK 3
• flash_point_f: 255.2 °F
• flash_point_c: 124 °C