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Supelco

Enoxacin sesquihydrate

analytical standard

Synonym(s):

1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-1,8-naphthyridine-3-carboxylic acid sesquihydrate

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About This Item

Empirical Formula (Hill Notation):
C15H17FN4O3 · 1.5H2O
CAS Number:
Molecular Weight:
347.34
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

analytical standard

Quality Level

assay

≥98.0% (HPLC)

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

impurities

≤15 wt. % water

solubility

1 M NaOH: 50 mg/mL, clear, colorless to faintly yellow

suitability

conforms to structure for Proton NMR spectrum

application(s)

clinical testing

format

neat

SMILES string

O.O.O.CCN1C=C(C(O)=O)C(=O)c2cc(F)c(nc12)N3CCNCC3.CCN4C=C(C(O)=O)C(=O)c5cc(F)c(nc45)N6CCNCC6

InChI

1S/2C15H17FN4O3.3H2O/c2*1-2-19-8-10(15(22)23)12(21)9-7-11(16)14(18-13(9)19)20-5-3-17-4-6-20;;;/h2*7-8,17H,2-6H2,1H3,(H,22,23);3*1H2

InChI key

DKNNITGJCMPHKE-UHFFFAOYSA-N

Application

Enoxacin sesquihydrate may be used as a reference standard for the determination of enoxacin in plasma by high-performance liquid chromatography.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

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Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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Simultaneous assay of fluoroquinolones and theophylline in plasma by high-performance liquid chromatography.
Davis JD, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 621(1), 105- 109 (1993)
Anna Margaret McDonnell et al.
Molecules (Basel, Switzerland), 24(8) (2019-04-25)
Cervical cancer is a major cause of death in females worldwide. While survival rates have historically improved, there remains a continuous need to identify novel molecules that are effective against this disease. Here, we show that enoxacin, a drug most
Julieta Griboff et al.
Food chemistry, 332, 127380-127380 (2020-07-01)
The occurrence of 46 antibiotics (amphenicols, cephalosporins, dihydrofolate reductase inhibitors, fluroquinolones, macrolides, nitrofurans, penicillins, quinolones, sulfamides and tetracyclines) in Argentinean market fish were investigated by UPLC-MS/MS. Veterinary and human antimicrobials enrofloxacin, clarithromycin, roxithromycin, doxycycline and oxytetracycline were detected in 100%

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