90948
(2S,3R)-2,3-Dihydroxybutyric acid sodium salt hydrate
≥97.0% (GC)
Synonym(s):
(2S,3R)-2,3-Dihydroxybutanoic acid sodium salt hydrate, 4-Deoxy-D-threonic acid sodium salt hydrate
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About This Item
Empirical Formula (Hill Notation):
C4H8O4 · xNa+ · yH2O
Molecular Weight:
120.10 (anhydrous free acid basis)
UNSPSC Code:
12352106
PubChem Substance ID:
NACRES:
NA.24
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![Poly[(R)-3-hydroxybutyric acid] natural origin](/deepweb/assets/sigmaaldrich/product/structures/129/476/7d1c924b-f644-4889-a2d6-d7a923ce382c/640/7d1c924b-f644-4889-a2d6-d7a923ce382c.png)
Quality Level
assay
≥97.0% (GC)
optical activity
[α]/D -27±3°, c = 0.5 in 0.1 M NaOH
application(s)
clinical testing
format
neat
storage temp.
2-8°C
Biochem/physiol Actions
(2S,3R)- 2,3-Dihydroxybutanoic acid is a normally occurring carboxylic acid in humans. Metabolic profiling of urinary organic acids from patients with Type 1 diabetes mellitus (juvenile-onset) have revealed significantly elevated levels of this metabolite. The normal urinary constituent (2S,3R)-2,3- dihydroxybutanoic acid was found to diminish in urine incubated with E. coli.
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
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Qun Liang et al.
Applied biochemistry and biotechnology, 176(8), 2170-2184 (2015-06-20)
Metabolomics is a post-genomics research field for analysis of low molecular weight compounds in biological samples and has shown great potentials for elucidating complex mechanisms associated with diseases. However, metabolomics studies on gastric cancer (GC), which is the second leading
Highly enantioselective reduction of ethyl 2-acyloxy-3-oxobutanoate with immobilized Baker's yeast.
Sakai, T., et al.
Bulletin of the Chemical Society of Japan, 59, 3185-3188 (1986)
Jian-Jun Chen et al.
Journal of proteome research, 14(8), 3382-3389 (2015-07-15)
Bipolar disorder (BD) is a complex debilitating mental disorder that is often misdiagnosed as major depressive disorder (MDD). Therefore, a large percentage of BD subjects are incorrectly treated with antidepressants in clinical practice. To address this challenge, objective laboratory-based tests
K Maeda et al.
Journal of chromatography, 345(1), 11-18 (1985-11-29)
For rapid identification of Escherichia coli, changes of urinary metabolites incubated with E. coli were investigated by gas chromatography--mass spectrometry. Hydroquinone and uracil were detected and the normal urinary constituent 4-deoxythreonic acid was found to diminish in urine incubated with
M Tuchman et al.
Journal of chromatographic science, 22(5), 198-202 (1984-05-01)
Gas chromatographic retention indices (methylene units) are reported for 101 urinary organic acids as their trimethylsilyl and oximated trimethylsilyl derivatives on a 5% phenylmethyl silicone fused silica capillary column. Using anion exchange chromatography, organic acids were extracted from urines of
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