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90567

Antipyrine

Name: Antipyrine
Brand: SIAL

analytical reference material

Synonym(s):

2,3-Dimethyl-1-phenyl-3-pyrazolin-5-one, Phenazone

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About This Item

Empirical Formula (Hill Notation):

C₁₁H₁₂N₂O

CAS Number:

60-80-0

Molecular Weight:

188.23

Beilstein/REAXYS Number:

157775

EC Number:

200-486-6

MDL number:

MFCD00003146

UNSPSC Code:

77101502

PubChem Substance ID:

329769926

This product is discontinued. Contact Technical Servicefor assistance.

grade

analytical reference material
reference material

assay

≥98.5% (qNMR)
≥99.0% (GC)

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

impurities

≤0.5% water

mp

109-111 °C (lit.)

application(s)

forensics and toxicology
pharmaceutical (small molecule)

format

neat

SMILES string

CN1N(C(=O)C=C1C)c2ccccc2

InChI

1S/C11H12N2O/c1-9-8-11(14)13(12(9)2)10-6-4-3-5-7-10/h3-8H,1-2H3

InChI key

VEQOALNAAJBPNY-UHFFFAOYSA-N

Gene Information

human ... PTGS1(5742)

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Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

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Certificates of Analysis (COA)

Lot/Batch Number

BCBK9017

BCBQ7463V

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[Evaluation of liver monooxygenase function by the kinetics of antipyrine and its metabolites in liquid media of the body].

L B Zavodnik et al.

Farmakologiia i toksikologiia, 52(3), 95-101 (1989-05-01)

The presented findings indicate that the determination in the blood or saliva of antipyrine concentration kinetics as well as the profile and the ratio of the products of its hydroxylation in the urine makes it possible to evaluate under clinical

Antipyrine as a model drug to study hepatic drug-metabolizing capacity.

H E Poulsen et al.

Journal of hepatology, 6(3), 374-382 (1988-06-01)

[The use of the antipyrine test for studying microsomal drug oxidation].

A P Viktorov et al.

Farmakologiia i toksikologiia, 53(1), 74-77 (1990-01-01)

The data about the use of "antipyrine test" in clinical practice for studying the drug oxidation peculiarities are presented. The data characterize the main pharmacokinetic properties of antipyrine as a "metabolic marker" for quantitative estimation of the effects of inductors

Factors influencing antipyrine elimination.

I H Stevenson

British journal of clinical pharmacology, 4(3), 261-265 (1977-06-01)

Measurement of blood flow with freely diffusible indicators as inert gases, antipyrine, labelled water and rubidium.

N A Lassen et al.

Acta endocrinologica. Supplementum, 158, 95-111 (1972-01-01)

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