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84211

Sigma-Aldrich

Salicylic acid

tested according to Ph. Eur.

Synonym(s):

Acidum salicylicum, 2-Hydroxybenzoic acid

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About This Item

Linear Formula:
2-(HO)C6H4CO2H
CAS Number:
Molecular Weight:
138.12
Beilstein/REAXYS Number:
774890
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.21

agency

USP/NF
tested according to Ph. Eur.

Quality Level

vapor density

4.8 (vs air)

vapor pressure

1 mmHg ( 114 °C)

bp

211 °C (lit.)

mp

158-161 °C (lit.)

SMILES string

OC(=O)c1ccccc1O

InChI

1S/C7H6O3/c8-6-4-2-1-3-5(6)7(9)10/h1-4,8H,(H,9,10)

InChI key

YGSDEFSMJLZEOE-UHFFFAOYSA-N

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General description

Salicylic acid is an aromatic phenolic derivative. It plays an important role in various physiological processes in plants, such as thermogenesis, ethylene synthesis and fruit ripening.

Application

Salicylic acid may be used for the quantitative estimation of nitrate in plant materials by colorimetric method. It may be used in the synthesis of 2,5-dihydroxybenzoic acid (gentistic acid).

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Danger

Hazard Classifications

Acute Tox. 4 Oral - Eye Dam. 1 - Repr. 2

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

314.6 °F - closed cup

flash_point_c

157 °C - closed cup

ppe

dust mask type N95 (US), Eyeshields, Gloves


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Rapid colorimetric determination of nitrate in plant tissue by nitration of salicylic acid1.
Cataldo DA, et al.
Communications in Soil Science and Plant Analysis, 6(1), 71-80 (1975)
Eagleson M.
Concise Encyclopedia Chemistry, 449-449 (1994)
Salicylic acid activates nitric oxide synthesis in Arabidopsis.
Zottini M, et al.
Journal of Experimental Botany, 58(6), 1397-1405 (2007)
S G Owen et al.
British journal of clinical pharmacology, 38(4), 349-355 (1994-10-01)
1. Five rheumatoid patients with a knee joint effusion participated in the study. An aqueous solution (0.1 to 0.2 ml) containing paracetamol, salicylate, diclofenac and [125I]-albumin was injected into a given joint to yield target concentrations of approximately 20 micrograms
Zheng Qing Fu et al.
Annual review of plant biology, 64, 839-863 (2013-02-05)
Systemic acquired resistance (SAR) is an induced immune mechanism in plants. Unlike vertebrate adaptive immunity, SAR is broad spectrum, with no specificity to the initial infection. An avirulent pathogen causing local programmed cell death can induce SAR through generation of

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