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Supelco

Phyllanthin

analytical standard

Synonym(s):

(2S,3S)-(+)-1,4-Dimethoxy-2,3-diveratrylbutane

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About This Item

Empirical Formula (Hill Notation):
C24H34O6
CAS Number:
Molecular Weight:
418.52
Beilstein/REAXYS Number:
2066503
MDL number:
UNSPSC Code:
85151701
PubChem Substance ID:
NACRES:
NA.24

grade

analytical standard

Quality Level

assay

≥95.0% (HPLC)

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

food and beverages

format

neat

SMILES string

COC[C@@H](Cc1ccc(OC)c(OC)c1)[C@@H](COC)Cc2ccc(OC)c(OC)c2

InChI

1S/C24H34O6/c1-25-15-19(11-17-7-9-21(27-3)23(13-17)29-5)20(16-26-2)12-18-8-10-22(28-4)24(14-18)30-6/h7-10,13-14,19-20H,11-12,15-16H2,1-6H3/t19-,20-/m1/s1

InChI key

KFLQGJQSLUYUBF-WOJBJXKFSA-N

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General description

Phyllanthin is found in many Phyllanthus species. It is a lignan compound which exhibits various biochemical and pharmacological properties.

Application

Phyllanthin may be used as a reference standard for the determination of the analyte in Phyllanthus species by high-performance thin layer chromatography (HPTLC).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

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Storage Class

13 - Non Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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Protective activity of phyllanthin in ethanol-treated primary culture of rat hepatocytes.
Chirdchupunseree H and Pramyothin P
Journal of Ethnopharmacology, 128(1), 172- 176 (2010)
Quantitative determination of phyllanthin and hypophyllanthin in Phyllanthus species by high-performance thin layer chromatography.
Tripathi AK, et al.
Phytochemical Analysis, 17(6), 394- 397 (2006)
Phyllanthin from Phyllanthus amarus inhibits cellular and humoral immune responses in Balb/C mice.
Ilangkovan M, et al.
Phytomedicine, 23(12), 1441- 1450 (2016)
Cong Zhao et al.
Environmental toxicology (2020-08-17)
Ischemic heart disease is an imperative cause of high morbidity and mortality globally. The cardiac ischemia/reperfusion damage occur in both reperfusion and ischemia. In this exploration, we have planned to examine the cardio-protective action of phyllanthin against the myocardial ischemic-reperfusion
Nguyen Duc Hanh et al.
Drug development and industrial pharmacy, 40(6), 793-802 (2013-04-19)
Phyllanthin is a major bioactive lignan component of Phyllanthus amarus, with several known biological activities. This study dealt with the isolation and physicochemical characterization of phyllanthin. Phyllanthin was isolated from P. amarus leaves by column chromatography and purified by recrystallization

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