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74711

Sigma-Aldrich

Ochratoxin A

purum, ≥98.0% (TLC), from Aspergillus ochraceus

Synonym(s):

N-[(3R)-(5-Chloro-8-hydroxy-3-methyl-1-oxo-7-isochromanyl)carbonyl]-L-phenylalanine

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About This Item

Empirical Formula (Hill Notation):
C20H18ClNO6
CAS Number:
303-47-9
Molecular Weight:
403.81
Beilstein/REAXYS Number:
1301486
EC Number:
206-143-7
MDL number:
MFCD00078079
UNSPSC Code:
12352200
PubChem Substance ID:
329765811
Pricing and availability is not currently available.

biological source

Aspergillus ochraceus

grade

purum

assay

≥98.0% (TLC)

form

powder

mode of action

enzyme | inhibits
protein synthesis | interferes

storage temp.

2-8°C

SMILES string

C[C@@H]1Cc2c(Cl)cc(c(O)c2C(=O)O1)C(=O)N[C@@H](Cc3ccccc3)C(O)=O

InChI

1S/C20H18ClNO6/c1-10-7-12-14(21)9-13(17(23)16(12)20(27)28-10)18(24)22-15(19(25)26)8-11-5-3-2-4-6-11/h2-6,9-10,15,23H,7-8H2,1H3,(H,22,24)(H,25,26)/t10-,15+/m1/s1

InChI key

RWQKHEORZBHNRI-BMIGLBTASA-N

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Other Notes

Inhibitor of mitochondrial transport systems[1]; Mode of action[2].

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R. Roschenthaler et al.
J. Toxicol.-Toxin Reviews, 3, 53-53 (1984)
Ochratoxin A, an inhibitor of mitochondrial transport systems.
H Meisner et al.
Biochemistry, 13(14), 2795-2800 (1974-07-02)
Donata Lerda et al.
Journal of AOAC International, 96(2), 331-340 (2013-06-19)
A collaborative study was conducted to validate an analytical method for the determination of ochratoxin A (OTA) in licorice (root powder) and licorice extracts (paste and powder). Contents of OTA ranged from 26 to 141 microg/kg and from 8 to
Yan Wang et al.
Plant molecular biology, 82(4-5), 321-337 (2013-04-30)
Ochratoxin A (OTA) is a mycotoxin that is primarily produced by Aspergillus ochraceus and Penicillium verrucosum. This mycotoxin is a contaminant of food and feedstock worldwide and may induce cell death in plants. To investigate the dynamic growth process of
C Frizzell et al.
Toxicology letters, 217(3), 243-250 (2013-01-09)
Ochratoxin A (OTA) is a mycotoxin and extrolite of fungi which has been reported in a range of foods. This study uses mammalian reporter gene assays (RGAs) with natural steroid receptors and the H295R steroidogenesis assay to assess the endocrine
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