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Key Documents

71943

Sigma-Aldrich

Sodium salicylate

tested according to Ph. Eur.

Synonym(s):

Natrii salicylas, 2-Hydroxybenzoic acid sodium salt, Salicylic acid sodium salt, Sodium 2-hydroxybenzoate

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About This Item

Linear Formula:
HOC6H4COONa
CAS Number:
Molecular Weight:
160.10
Beilstein/REAXYS Number:
3732792
EC Number:
MDL number:
UNSPSC Code:
12352201
PubChem Substance ID:
NACRES:
NA.21

agency

USP/NF
tested according to Ph. Eur.

Quality Level

form

crystals

color

white

useful pH range

6.85 (26.3 °C)

mp

>300 °C (lit.)

solubility

water: 575.7 g/L at 25 °C (77 °F)

application(s)

pharmaceutical (small molecule)

SMILES string

[Na+].Oc1ccccc1C([O-])=O

InChI

1S/C7H6O3.Na/c8-6-4-2-1-3-5(6)7(9)10;/h1-4,8H,(H,9,10);/q;+1/p-1

InChI key

ABBQHOQBGMUPJH-UHFFFAOYSA-M

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pictograms

Health hazardExclamation mark

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Repr. 2

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

208.9 °F - Pensky-Martens closed cup

flash_point_c

98.3 °C - Pensky-Martens closed cup

ppe

dust mask type N95 (US), Eyeshields, Gloves


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Kui Wang et al.
Journal of medicinal chemistry, 52(20), 6402-6412 (2009-10-16)
Viologens are showing an increasing number of scientific and technical applications in addition to their use as herbicides. However, their high toxicity poses considerable risks to human health, society, and the environment. In this context, we propose a new therapeutic
Astam K Patra et al.
Journal of hazardous materials, 201-202, 170-177 (2011-12-16)
We report a highly efficient synthetic strategy for self-assembled mesoporous γ-Al(2)O(3) materials using sodium salicylate as template. The mesoporous γ-Al(2)O(3) samples synthesized following this strategy have high surface areas (231-497 m(2)g(-1)), consist of crystalline tiny spherical nanoparticles of dimensions ca.
Yan-Yan Su et al.
PloS one, 7(10), e46969-e46969 (2012-10-17)
Sodium salicylate (NaSal), an aspirin metabolite, can cause tinnitus in animals and human subjects. To explore neural mechanisms underlying salicylate-induced tinnitus, we examined effects of NaSal on neural activities of the medial geniculate body (MGB), an auditory thalamic nucleus that
Guang-Di Chen et al.
Hearing research, 295, 100-113 (2012-12-04)
High doses of sodium salicylate (SS) have long been known to induce temporary hearing loss and tinnitus, effects attributed to cochlear dysfunction. However, our recent publications reviewed here show that SS can induce profound, permanent, and unexpected changes in the
Qian Zhang et al.
Acta biomaterialia, 8(3), 1316-1322 (2011-12-14)
Poly(amidoamine) (PAMAM) dendrons were prepared from hollow fiber membranes (HFM) consisting of bromomethylated poly(2,6-dimethyl-1,4-phenylene oxide) (BPPO) in a stepwise manner. The prepared HFM were characterized by Fourier transform infrared spectroscopy, elemental analysis, and scanning electron microscopy. The drug loading efficiency

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