71480

Sodium diethyldithiocarbamate trihydrate

ACS reagent, for the determination and separation of heavy metals, ≥97%

• Synonym(s): Cupral, Diethyldithiocarbamic acid sodium salt
• Linear Formula: (C₂H₅)₂NCSSNa · 3H₂O
• CAS Number: 20624-25-3
• Molecular Weight: 225.31
• Beilstein/REAXYS Number: 3920507
• EC Number: 205-710-6
• MDL number: MFCD00150617
• UNSPSC Code: 12000000
• PubChem Substance ID: 57652304
• NACRES: NA.21

Properties

• grade: ACS reagent
• Quality Level: 200
• vapor density: 5.9 (vs air)
• assay: ≥97%
• form: powder
• quality: for the determination and separation of heavy metals
• mp: 95-98.5 °C (lit.)
• cation traces: Cd: ≤5 mg/kg; Co: ≤5 mg/kg; Cr: ≤5 mg/kg; Cu: ≤5 mg/kg; Fe: ≤5 mg/kg; Mn: ≤5 mg/kg; Ni: ≤5 mg/kg; Pb: ≤5 mg/kg; Zn: ≤5 mg/kg
• SMILES string: [H]O[H].[H]O[H].[H]O[H].CCN(CC)C(=S)S[Na]
• InChI: 1S/C5H11NS2.Na.3H2O/c1-3-6(4-2)5(7)8;;;;/h3-4H2,1-2H3,(H,7,8);;3*1H2/q;+1;;;/p-1
• InChI key: WWGXHTXOZKVJDN-UHFFFAOYSA-M

Description

General description

Sodium diethyldithiocarbamate trihydrate is a chelating agent, generally used in mobilizing toxic metals from the human tissues and experimental animals. It exists as a white or colorless solid, and is freely soluble with gradual decomposition.

Application

Sodium diethyldithiocarbamate trihydrate was used during the synthesis of N-allylpeptides, in a study outlining the strategy to synthesize and purify a hydrogen bond surrogate (HBS) α-helix in ∼1 week.

Spin trap used in conjunction with Fe²⁺ to detect NO in brain, kidney, liver, and other tissues. Simultaneous direct measurement of NO* and pO₂ has been reported. A copper chelator, it has been used to quantitate copper in biological materials by ESR and is an inhibitor of superoxide dismutase, ascorbate oxidase, and other enzymes.

Biochem/physiol Actions

Inhibits induction of macrophage nitric oxide synthase.

Other Notes

Reagent used for the extraction of trace metals into organic solvents for atomic absorption spectroscopy; Precipitation of trace metals for x-ray fluorescence spectroscopy

Safety Information

• pictograms: GHS05,GHS07
• signalword: Danger
• hcodes: H302,H315,H318
• pcodes: P264 - P270 - P280 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Eye Dam. 1 - Skin Irrit. 2
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves