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Supelco

Magnesium ionophore II

Selectophore™, function tested

Synonym(s):

ETH 5214, N,N′′-Octamethylene-bis(N′-heptyl-N′-methyl-methylmalonamide

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About This Item

Empirical Formula (Hill Notation):
C32H62N4O4
CAS Number:
119110-37-1
Molecular Weight:
566.86
Beilstein/REAXYS Number:
6018631
MDL number:
MFCD00144714
UNSPSC Code:
26111700
PubChem Substance ID:
329759776
NACRES:
NB.61

grade

for ion-selective electrodes

Quality Level

200

product line

Selectophore™

quality

function tested

mp

63-65 °C

SMILES string

CCCCCCCN(C)C(=O)C(C)C(=O)NCCCCCCCCNC(=O)C(C)C(=O)N(C)CCCCCCC

InChI

1S/C32H62N4O4/c1-7-9-11-17-21-25-35(5)31(39)27(3)29(37)33-23-19-15-13-14-16-20-24-34-30(38)28(4)32(40)36(6)26-22-18-12-10-8-2/h27-28H,7-26H2,1-6H3,(H,33,37)(H,34,38)

InChI key

UTFJQHTUZRJEKD-UHFFFAOYSA-N

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General description

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Other Notes

New synthetic neutral ionophore for magnesium. Assay of Mg2+-activity in intracellular liquids with microelectrodes based on Magnesium Ionophore II

Legal Information

Selectophore is a trademark of Merck KGaA, Darmstadt, Germany

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
SLBG6212
061236/1
61236/1

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A Buri et al.
Experimental physiology, 75(6), 751-761 (1990-11-01)
Intracellular free magnesium ([Mg2+]i) was measured in isolated ferret papillary muscles using ion-selective microelectrodes filled with the new magnesium sensor ETH 5214. This new sensor, unlike its predecessor ETH 1117, does not react to marked changes in K+, Na+ or
L A Blatter
Pflugers Archiv : European journal of physiology, 416(3), 238-246 (1990-05-01)
The application of a new type of intracellular magnesium-selective microelectrode based on the neutral carrier ETH5214 to measure intracellular free magnesium ([Mg]i) in frog skeletal muscle fibers is reported. At room temperature (18-20 degrees C) the average values for [Mg]i
Z M Hu et al.
Analytical chemistry, 61(6), 574-576 (1989-03-15)
A magnesium ion selective microelectrode based on a synthetic neutral carrier is presented. The selectivity of Mg2+ over Na+, K+, H+, and Ca2+ is sufficient for assays of intracellular magnesium ion activities. The microelectrodes with an optimized membrane composition have
Mathieu Métivier et al.
Current biology : CB, 31(4), 684-695 (2020-12-02)
Proper assembly of mitotic spindles requires microtubule nucleation not only at the centrosomes but also around chromatin. In this study, we found that the Drosophila tubulin-specific chaperone dTBCE is required for the enrichment of tubulin in the nuclear space after

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