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55070

Sigma-Aldrich

8-Quinolinol

puriss. p.a., ACS reagent, for the detection and determination of Al, Mg and others, ≥99.0% (NT)

Synonym(s):

8-Hydroxyquinoline, 8-Oxychinolin, Oxine

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About This Item

Empirical Formula (Hill Notation):
C9H7NO
CAS Number:
148-24-3
Molecular Weight:
145.16
Beilstein/REAXYS Number:
114512
EC Number:
205-711-1
MDL number:
MFCD00006807
UNSPSC Code:
12352100
PubChem Substance ID:
329758074

grade

ACS reagent
puriss. p.a.

assay

≥99.0% (NT)

quality

for the detection and determination of Al, Mg and others

mp

72.5-74 °C
72.5-74.0 °C

antibiotic activity spectrum

fungi

mode of action

DNA synthesis | interferes
enzyme | inhibits

SMILES string

Oc1cccc2cccnc12

InChI

1S/C9H7NO/c11-8-5-1-3-7-4-2-6-10-9(7)8/h1-6,11H

InChI key

MCJGNVYPOGVAJF-UHFFFAOYSA-N

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General description

Chemical structure: quinolone

signalword

Danger

Hazard Classifications

Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Repr. 1B - Skin Sens. 1

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

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Synthesis, crystal structure and spectral properties of VO (acetylacetone benzoylhydrazone)(8-quinolinol).
Liu SX and Gao S.
Polyhedron, 17(1), 81-84 (1998)
The reactions of 8-quinolinol.
Phillips JP.
Chemical Reviews, 56(2), 271-297 (1956)
Synthesis of silica-immobilized 8-quinolinol with (aminophenyl) trimethoxysilane.
Marshall MA and Mottola HA.
Analytical Chemistry, 55(13), 2089-2093 (1983)
Phosphorescent 8-quinolinol metal chelates. Excited-state properties and redox behavior.
Ballardini R, et al.
Inorganic Chemistry, 25(22), 3858-3865 (1986)
Erik H J G Aarntzen et al.
Clinical cancer research : an official journal of the American Association for Cancer Research, 19(6), 1525-1533 (2013-02-06)
Anticancer dendritic cell (DC) vaccines require the DCs to relocate to lymph nodes (LN) to trigger immune responses. However, these migration rates are typically very poor. Improving the targeting of ex vivo generated DCs to LNs might increase vaccine efficacy
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