48940

Gitoxigenin

≥98.0% (HPLC)

• Synonym(s): 16β-Hydroxydigitoxigenin, 3β,14,16β,21-Tetrahydroxy-20(22)-norcholenic acid lactone, 3β,14,16β-Trihydroxy-5β,20(22)-cardenolide, 5β,20(22)-Cardenolide-3β,14,16β-triol
• Empirical Formula (Hill Notation): C₂₃H₃₄O₅
• CAS Number: 545-26-6
• Molecular Weight: 390.51
• UNSPSC Code: 12352200
• EC Number: 208-886-2
• Beilstein/REAXYS Number: 96483
• MDL number: MFCD00021174

Properties

• SMILES string: [H][C@]12CC[C@]3([H])[C@]([H])(CC[C@]4(C)[C@H]([C@@H](O)C[C@]34O)C5=CC(=O)OC5)[C@@]1(C)CC[C@H](O)C2
• assay: ≥98.0% (HPLC)
• optical activity: [α]20/D +30±2°, c = 1% in methanol
• mp: ~230 °C

Description

Biochem/physiol Actions

Structure-activity relationships for 16β-substituted digitoxigenins as inhibitors of Na⁺/K⁺ ATPases.