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46174

Supelco

Diaveridine

VETRANAL®, analytical standard

Synonym(s):

5-(3,4-Dimethoxybenzyl)-2,4-pyrimidinediamine

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About This Item

Empirical Formula (Hill Notation):
C13H16N4O2
CAS Number:
5355-16-8
Molecular Weight:
260.29
Beilstein/REAXYS Number:
258464
EC Number:
226-333-3
MDL number:
MFCD00057349
UNSPSC Code:
41116107
PubChem Substance ID:
329757094
NACRES:
NA.24

grade

analytical standard

Quality Level

200

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

clinical testing

format

neat

storage temp.

2-8°C

SMILES string

COc1ccc(Cc2cnc(N)nc2N)cc1OC

InChI

1S/C13H16N4O2/c1-18-10-4-3-8(6-11(10)19-2)5-9-7-16-13(15)17-12(9)14/h3-4,6-7H,5H2,1-2H3,(H4,14,15,16,17)

InChI key

LDBTVAXGKYIFHO-UHFFFAOYSA-N

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Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

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Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 2

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCCC9436

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D S Lindsay et al.
American journal of veterinary research, 57(1), 68-72 (1996-01-01)
To examine the efficacies of combinations of 7 sulfonamides and 5 dihydrofolate reductase/thymidylate synthase (DHFR/TS) inhibitors against tachyzoites of Neospora caninum in cultured cells. Mutant tachyzoites that were resistant to pyrimethamine were produced and examined for resistance to other DHFR/TS
Zhao-Ying Liu et al.
Biomedical chromatography : BMC, 26(9), 1101-1108 (2011-12-14)
Trimethoprim (TMP) and diaveridine (DVD) are used in combination with sulfonamides and sulfaquinoxlaine as an effective antibacterial agent and antiprotozoal agent, respectively, in humans and animals. To gain a better understanding of the metabolism of TMP and DVD in the
G Gigler et al.
Agents and actions. Supplements, 32, 39-43 (1991-01-01)
The compound EGIS-5645 is a potent antipyretic agent possessing analgesic and antiinflammatory properties. The drug is active in antiinflammatory models such as carrageenin oedema and adjuvant arthritis. EGIS-5645 shows practically no gastro-ulcerogenic effect. The molecule does not inhibit either prostaglandin
H Yoshimura
Mutation research, 261(2), 149-152 (1991-10-01)
The coccidiostat diaveridine was tested for mutagenicity in the Salmonella/microsome assay with tester strains TA100 and TA98. This compound was not mutagenic in either tester strain in the presence and absence of rat S9 mix, but was found to be
P D Walzer et al.
Antimicrobial agents and chemotherapy, 32(1), 96-103 (1988-01-01)
Inhibitors of folic acid synthesis were compared alone and in different combinations in the therapy of pneumocystosis in immunosuppressed rats. Sulfonamides (sulfamethoxazole, sulfadiazine, and sulfadoxine) and sulfones (dapsone) used alone were very active against Pneumocystis carinii, as judged by histologic
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