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Salidroside

analytical standard

Synonym(s):

2-(4-Hydroxyphenyl)ethyl β−D-glucopyranoside, p-Hydroxyphenethyl glucopyranoside, Rhodioloside, Rhodosin, Tyrosol a-(β-D-glucopyranoside)

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25 MG
$272.00

$272.00

Available to ship onApril 29, 2025Details

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25 MG
$272.00

About This Item

Empirical Formula (Hill Notation):
C14H20O7
CAS Number:
10338-51-9
Molecular Weight:
300.30
MDL number:
MFCD00210553
UNSPSC Code:
85151701
PubChem Substance ID:
329756416
NACRES:
NA.24

$272.00

Available to ship onApril 29, 2025Details

Request a Bulk Order

grade

analytical standard

Quality Level

100

assay

≥98.0% (HPLC)

optical activity

[α]/D -29±2°, c = 0.5 in methanol

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

food and beverages

format

neat

SMILES string

OC[C@H]1O[C@@H](OCCc2ccc(O)cc2)[C@H](O)[C@@H](O)[C@@H]1O

InChI

1S/C14H20O7/c15-7-10-11(17)12(18)13(19)14(21-10)20-6-5-8-1-3-9(16)4-2-8/h1-4,10-19H,5-7H2/t10-,11-,12+,13-,14-/m1/s1

InChI key

ILRCGYURZSFMEG-RKQHYHRCSA-N

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General description

Salidroside is one of the major phenolic glycoside extracted from Rhodiola rosea L([1], which can show a broad-spectrum of pharmacological properties like anti-aging, anti-oxidant, anti-cancer and anti-inflammation.[2][1][3]

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem/physiol Actions

Salidroside, the 8-O-β-D-glucoside of tyrosol, is the main bioactive component of Rhodiola species and is found mainly in the plant roots. It is biosynthesised in the tyrosine metabolism, with glucosylation of tyrosol being the final step[4]. It has been reported to be neuroprotective[2] [5][3] and one of the compounds responsible for the antidepressant and anxiolytic actions of Rhodiola rosea[6][7].

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H319

Hazard Classifications

Eye Irrit. 2

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
BCCM4309
BCCL2086
BCCH2071
BCCD9981
BCCC1278

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Salidroside decrease expression of hypoxia-inducible factor-1α in cultured human lung cancer cells.
Li, B., et al.
African Journal of Pharmacy and Pharmacology, 34, 2526-2530 (2012)
Erin Wei Qian et al.
Journal of natural products, 75(4), 531-537 (2012-04-10)
Rhodiola rosea is a commonly used folk medicine for the treatment of high altitude sickness, mountain malhypoxia, and anoxia. Its active ingredient, salidroside [2-(4-hydroxyphenyl)ethyl β-D-glucopyranoside (1)], has been reported to have a broad spectrum of biological effects. However, the protective
Li Zhang et al.
European journal of pharmacology, 564(1-3), 18-25 (2007-03-14)
Oxidative stress plays an important role in Alzheimer's disease and other neurodegenerative disorders. Salidroside, a phenylpropanoid glycoside isolated from Rhodiola rosea L, shows potent antioxidant property. In this paper, the neuroprotective effects of salidroside on hydrogen peroxide (H2O2)-induced apoptosis in
Li Zhang et al.
Neurochemistry international, 57(5), 547-555 (2010-07-10)
Beta-amyloid (Abeta) peptide, the hallmark of Alzheimer's disease (AD), invokes a cascade of oxidative damages to neurons and eventually leads to neuronal death. In this study, salidroside (Sald), an active compound isolated from a traditional Chinese medicinal plant, Rhodiola rosea
Depeng Li et al.
Inflammation research : official journal of the European Histamine Research Society ... [et al.], 62(1), 9-15 (2012-08-24)
Mastitis is defined as inflammation of the mammary gland in domestic dairy animals and humans. Salidroside, a major component isolated from Rhodiola rosea L., has potent anti-inflammatory properties, but whether it can be used in mastitis treatment has not yet
View All Related Papers

Questions

1–2 of 2 Questions  

  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

      Helpful?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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