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42734

Supelco

Genkwanin

analytical standard

Synonym(s):

4′,5-Dihydroxy-7-methoxyflavone, 5-Hydroxy-2-(4-hydroxyphenyl)-7-methoxy-4H-1-benzopyran-4-one, 7-O-Methylapigenin, Apigenin 7-O-methyl ether, Puddumetin

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About This Item

Empirical Formula (Hill Notation):
C16H12O5
CAS Number:
437-64-9
Molecular Weight:
284.26
Beilstein/REAXYS Number:
292549
MDL number:
MFCD00017452
UNSPSC Code:
12352200
PubChem Substance ID:
329756263
NACRES:
NA.24

grade

analytical standard

assay

≥98.0% (HPLC)

shelf life

limited shelf life, expiry date on the label

application(s)

food and beverages

format

neat

storage temp.

−20°C

InChI

1S/C16H12O5/c1-20-11-6-12(18)16-13(19)8-14(21-15(16)7-11)9-2-4-10(17)5-3-9/h2-8,17-18H,1H3

InChI key

JPMYFOBNRRGFNO-UHFFFAOYSA-N

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General description

Genkwanin, an O-methylated flavone, is a principal non-glycosylated flavonoid present in several plant species; typically in herbs that exhibit anti-inflammatory activities.[1][2]

Application

Genkwanin may be used as an analytical standard for the determination of the analyte in biological samples,[3][4] traditional Chinese medicine,[5] rosemary (Rosmarinus officinalis) extract[6] and honey samples[7] by various chromatography techniques.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
BCCF2063
BCBZ9257
BCBR7201V
BCBR7201

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Liquid chromatograpic-mass spectrometric analysis of phenolics and free radical scavenging activity of rosemary extract from different raw material
Almela L, et al.
Journal of Chromatography A, 1120(1-2), 221-229 (2006)
Jiangbo Fan et al.
Pharmaceutical biology, 54(2), 279-284 (2015-04-11)
Leonurus artemisia (Lour.) S.Y.Hu (Lamiaceae) (YiMuCao in Chinese) is a traditional Chinese medicine. Leonurus artemisia has been shown to have many pharmacological effects such as increasing uterine contraction amplitude, and tension, but the active components are still unknown. The objective
Lin Yuan et al.
Xenobiotica; the fate of foreign compounds in biological systems, 48(4), 332-341 (2017-04-19)
Hydroxygenkwanin (HYGN) and genkwanin (GN) are major constituents of Genkwa Flos for the treatment of edema, ascites, cough, asthma and cancer. This is a report about the investigation of the metabolic fate of HYGN and GN in human liver microsomes
Pilar Truchado et al.
Journal of chromatography. A, 1216(43), 7241-7248 (2009-08-18)
HPLC-MS-MS analysis of unifloral honey extracts has shown the occurrence of flavonoid glycosides in most of the analyzed samples. These compounds are not present in large amounts, but can reach up to 600 microg/100g honey in canola and rapeseed honeys.
Yanqing Song et al.
Journal of pharmaceutical and biomedical analysis, 84, 129-134 (2013-07-09)
We developed and validated a sensitive, rapid, and specific liquid chromatography tandem mass spectrometry method to determine genkwanin in rat plasma. Genistein was used as the internal standard. After liquid-liquid extraction with ethyl acetate, the chromatographic separation of genkwanin was
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