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41620

Sigma-Aldrich

Dimethyl sulfate

purum, ≥95.0% (GC)

Synonym(s):

Sulfuric acid dimethyl ester

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About This Item

Linear Formula:
(CH3O)2SO2
CAS Number:
Molecular Weight:
126.13
Beilstein/REAXYS Number:
635994
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:

vapor density

4.3 (vs air)

vapor pressure

0.7 mmHg ( 25 °C)

grade

purum

assay

≥95.0% (GC)

autoignition temp.

923 °F

refractive index

n20/D 1.386 (lit.)
n20/D 1.387

bp

188 °C (lit.)

mp

−32 °C (lit.)

density

1.333 g/mL at 25 °C (lit.)

SMILES string

COS(=O)(=O)OC

InChI

1S/C2H6O4S/c1-5-7(3,4)6-2/h1-2H3

InChI key

VAYGXNSJCAHWJZ-UHFFFAOYSA-N

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Danger

Hazard Classifications

Acute Tox. 2 Inhalation - Acute Tox. 3 Oral - Carc. 1B - Eye Dam. 1 - Muta. 2 - Skin Corr. 1B - Skin Sens. 1

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk_germany

WGK 3

flash_point_f

181.4 °F - closed cup

flash_point_c

83 °C - closed cup

ppe

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter


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J D McGhee et al.
Proceedings of the National Academy of Sciences of the United States of America, 76(5), 2133-2137 (1979-05-01)
We have measured the effect of the histones in the nucleosome core particle on methylation of purines in nucleosome DNA by dimethyl sulfate. By using 32P terminally labeled nucleosome cores, we have examined the pattern of strand cleavage at methylated
M L Lee et al.
Science (New York, N.Y.), 207(4427), 186-188 (1980-01-11)
Dimethyl sulfate and its hydrolysis product monomethyl sulfate have been found at concentrations as high as 830 parts per million in fly ash and in airborne particulate matter from coal combustion processes. This discovery poses a new environmental problem because
Kwang Sun Ryu et al.
The journal of physical chemistry. B, 111(4), 731-739 (2007-01-26)
The physical properties of polyaniline (PAn) powder, doped by nucleophilic doping of dimethyl sulfate (DMS), were characterized, as well as its electrochemical behaviors, to investigate the possibility of a power source device adopting the PAn-DMS electrodes. It is shown that
Li Z Luo et al.
PloS one, 7(3), e30541-e30541 (2012-03-14)
The potential for human disease treatment using human pluripotent stem cells, including embryonic stem cells and induced pluripotent stem cells (iPSCs), also carries the risk of added genomic instability. Genomic instability is most often linked to DNA repair deficiencies, which
Jie Zheng et al.
Journal of pharmaceutical and biomedical analysis, 50(5), 1054-1059 (2009-07-07)
Dimethyl sulfate (DMS) is an alkylating reagent commonly used in organic syntheses and pharmaceutical manufacturing processes. Due to its potential carcinogenicity, the level of DMS in the API process needs to be carefully monitored. However, in-process testing for DMS is

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