38171

6-Mercaptopurine

analytical standard

• Synonym(s): 6-Purinethiol, 6-Thiohypoxanthine
• Empirical Formula (Hill Notation): C₅H₄N₄S
• CAS Number: 50-44-2
• Molecular Weight: 152.18
• EC Number: 200-037-4
• MDL number: MFCD00599524
• UNSPSC Code: 12352200
• PubChem Substance ID: 329755748

Properties

• grade: analytical standard
• Quality Level: 100
• assay: ≥98.0% (HPLC)
• shelf life: limited shelf life, expiry date on the label
• storage condition: under inert gas (argon)
• technique(s): HPLC: suitable; gas chromatography (GC): suitable
• impurities: ≤20% water
• application(s): pharmaceutical
• format: neat
• SMILES string: S=C1NC=NC2=C1NC=N2
• InChI: 1S/C5H4N4S/c10-5-3-4(7-1-6-3)8-2-9-5/h1-2H,(H2,6,7,8,9,10)
• InChI key: GLVAUDGFNGKCSF-UHFFFAOYSA-N
• Gene Information: human ... PPAT(5471)

Description

General description

6-Mercaptopurine (6-MP) is a purine analog, frequently prescribed for treating childhood acute lymphoblastic leukemia. It is also extensively used in the treatment of corticosteroid dependent inflammatory bowel disease (IBD) or the Crohn′s disease.[1][2]

Application

6-Mercaptopurine (6-MP) may be used as an analytical reference standard for the determination of the analyte in biological samples[3][4] by high-performance liquid chromatography (HPLC) technique.

Recommended products

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Safety Information

• pictograms: GHS06,GHS08
• signalword: Danger
• hcodes: H301,H341,H361fd
• pcodes: P202 - P264 - P280 - P301 + P310 - P405 - P501
• Hazard Classifications: Acute Tox. 3 Oral - Muta. 2 - Repr. 2
• Storage Class: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk_germany: WGK 3