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37906

Supelco

Methacycline hydrochloride

VETRANAL®, analytical standard

Synonym(s):

6-Demethyl-6-deoxy-6-methyleneoxytetracycline monohydrochloride

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About This Item

Empirical Formula (Hill Notation):
C22H22N2O8 · HCl
CAS Number:
3963-95-9
Molecular Weight:
478.88
Beilstein/REAXYS Number:
5470951
EC Number:
223-568-3
MDL number:
MFCD04972012
UNSPSC Code:
41116107
PubChem Substance ID:
329755720

grade

analytical standard

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

clinical testing

format

neat

SMILES string

Cl[H].[H][C@@]12[C@@H](O)[C@]3([H])C(=C)c4cccc(O)c4C(=O)C3=C(O)[C@]1(O)C(=O)C(C(N)=O)=C(O)[C@H]2N(C)C

InChI

1S/C22H22N2O8.ClH/c1-7-8-5-4-6-9(25)11(8)16(26)12-10(7)17(27)14-15(24(2)3)18(28)13(21(23)31)20(30)22(14,32)19(12)29;/h4-6,10,14-15,17,25,27-29,32H,1H2,2-3H3,(H2,23,31);1H/t10-,14-,15+,17+,22+;/m1./s1

InChI key

VZQARNDJLLWXGL-CCHMMTNSSA-N

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General description

Chemical structure: tetracycline

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

11 - Combustible Solids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
BCBZ0890

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E C Gil et al.
Electrophoresis, 22(3), 497-502 (2001-03-22)
The development and validation of an optimized capillary electrophoresis method for the determination of metacycline in the presence of its related substances by capillary electrophoresis is shown. The influence of methanol as organic modifier, buffer pH, buffer concentration, capillary length
M Tod et al.
Computer methods and programs in biomedicine, 50(1), 13-22 (1996-06-01)
The most common approach to optimize the sampling schedule in parameter estimation experiments is the D-optimality criterion, which consists in maximizing the determinant of the Fisher information matrix (max det F). In order to incorporate prior parameter uncertainty in the
Xian Xiang Sun et al.
Analytical sciences : the international journal of the Japan Society for Analytical Chemistry, 23(2), 231-233 (2007-02-14)
An internal solid contact sensor (ISCS) for the determination of methacycline hydrochloride (MC.Cl), Pt/PPy/PVC(MC-PT), is described, based on the use of conducting poly(pyrrole) (PPy) as solid contact material and MC-phosphotungstate (PT) as the ion exchanger and dibutyl phthalate (DBP) as
B Dubois et al.
Multiple sclerosis (Houndmills, Basingstoke, England), 4(2), 74-78 (1998-05-26)
The serine proteinase tissue-type plasminogen activator (t-PA) and the metalloproteinase gelatinase B (MMP-9) have recently been demonstrated in MS lesions. Both enzymes are interconnected in an enzyme cascade which contributes to destruction of the blood brain barrier and demyelination and
I Kruk et al.
Journal of photochemistry and photobiology. B, Biology, 14(4), 329-343 (1992-07-30)
Chemiluminescence (CL) appearing during autoxidation of tetracycline (TC) antibiotics has been studied. The CL spectrum consists of four emission bands with maxima at 520, 585, 640 and 700 nm. The bands at 585, 640 and 700 nm are similar to
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