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Supelco

EPN

100 μg/mL in acetonitrile, PESTANAL®, analytical standard

Synonym(s):

O-Ethyl O-(4-nitrophenyl) phenylphosphonothioate solution

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About This Item

CAS Number:
2104-64-5
Beilstein/REAXYS Number:
2542580
EC Number:
200-835-2
MDL number:
MFCD00055309
UNSPSC Code:
41116107
PubChem Substance ID:
329755563
NACRES:
NA.24

grade

analytical standard

product line

PESTANAL®

shelf life

limited shelf life, expiry date on the label

concentration

100 μg/mL in acetonitrile

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

agriculture

format

single component solution

storage temp.

2-8°C

SMILES string

CCOP(=S)(Oc1ccc(cc1)[N+]([O-])=O)c2ccccc2

InChI

1S/C14H14NO4PS/c1-2-18-20(21,14-6-4-3-5-7-14)19-13-10-8-12(9-11-13)15(16)17/h3-11H,2H2,1H3

InChI key

AIGRXSNSLVJMEA-UHFFFAOYSA-N

General description

EPN belongs to the class of organophosphorus insecticides extensively used in agriculture for the control of a wide range of insect pests.[1][2] Its mode of action involves the inhibition of acetylcholinesterase activity in insects.[2]

Application

EPN may be used as an analytical reference standard for the quantification of the analyte in tea[3] and environmental[1] samples using various chromatography techniques.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

PESTANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

FlameExclamation mark
GHS02,GHS07

signalword

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2

Storage Class

3 - Flammable liquids

wgk_germany

WGK 2

flash_point_f

35.6 °F

flash_point_c

2 °C

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

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Certificates of Analysis (COA)

Lot/Batch Number
BCBW6021

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Analysis of organophosphorus insecticides from environmental samples using solid-phase microextraction
Magdic S, et al.
Journal of Chromatography A, 736(1-2), 219-228 (1996)
Simultaneous multi-determination and transfer of eight pesticide residues from green tea leaves to infusion using gas chromatography
Cho K-S, et al.
Food Chemistry, 165, 532-539 (2014)
Development of enzyme-linked immunosorbent assays for the organophosphorus insecticide EPN
Shim YJ, et al.
Journal of Agricultural and Food Chemistry, 56(24), 11551-11559 (2008)
S Sugiyama et al.
Japanese journal of pharmacology, 37(3), 245-252 (1985-03-01)
O-Ethyl O-p-nitrophenyl phenylphosphonothioate (EPN)-induced inhibition of rat liver microsomal carboxylesterase (CEase) and formation of O-ethyl O-p-nitrophenyl phenylphosphonate (EPNoxon), an oxygen analog of EPN, were enhanced remarkably by addition of NAD in vitro. This potentiation of the anti-CEase action of EPN
M B Abou-Donia et al.
The Journal of pharmacology and experimental therapeutics, 257(1), 282-289 (1991-04-01)
The joint neurotoxic action of simultaneous exposure to vapors of n-hexane and methyl iso-butyl ketone (MiBK) and dermally applied O-ethyl O-nitrophenyl phenylphosphonothioate (EPN) was studied in groups of five adult hens. Four groups of hens were concurrently exposed to a
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