34536

Pirimiphos-methyl-(O,O-dimethyl-d₆)

PESTANAL^®, analytical standard

• Synonym(s): 2-Diethylamino-6-methylpyrimidin-4-yl-O,O-dimethyl-d₆-phosphorothioate, Pirimiphos-methyl-d₆
• Empirical Formula (Hill Notation): C₁₁D₆H₁₄N₃O₃PS
• Molecular Weight: 311.37
• MDL number: MFCD08273892
• UNSPSC Code: 77101502
• PubChem Substance ID: 329755023
• NACRES: NA.24

Properties

• grade: analytical standard
• Quality Level: 100
• product line: PESTANAL^®
• shelf life: limited shelf life, expiry date on the label
• application(s): agriculture
• format: neat
• storage temp.: 2-8°C
• SMILES string: CC1=NC(N(CC)CC)=NC(OP(OC([2H])([2H])[2H])(OC([2H])([2H])[2H])=S)=C1
• InChI: 1S/C11H20N3O3PS/c1-6-14(7-2)11-12-9(3)8-10(13-11)17-18(19,15-4)16-5/h8H,6-7H2,1-5H3/i4D3,5D3
• InChI key: QHOQHJPRIBSPCY-RKAHMFOGSA-N

Description

General description

Pirimiphos-methyl-(O,O-dimethyl-d₆) is a deuterated analog of pirimiphos-methyl, an organophosphorus insecticide, wherein the O-methyl protons are substituted by deuterium.

Application

Pirimiphos-methyl-(O,O-dimethyl-d₆) may be used as a deuterated internal standard to quantify pesticides in wheat flour and wastewater by ultra-high performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS) and HPLC-MS/MS, respectively.
Isotope-labeled compounds are increasingly used in isotope dilution mass spectrometry (IDMS) for the quantitative analysis of pesticides. The major advantage of using this technique is that the isotope-labeled compounds have nearly the same physical properties as their non-labeled counterpart analogs, and thus show identical behavior during the workup and sample preparation process. This helps in overcoming the problems of matrix effects generally encountered in the usual LC-MS/GC-MS analysis potentially resulting in biased results. By spiking the sample before workup with its isotope labeled analog, the loss of analyte that leads to matrix effects can be determined and compensated.

Legal Information

PESTANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• pictograms: GHS07,GHS09
• signalword: Warning
• hcodes: H302,H410
• pcodes: P273 - P301 + P312 + P330
• Hazard Classifications: Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1
• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable