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Supelco

Tilmicosin

VETRANAL®, analytical standard, mix of isomers

Synonym(s):

20-Deoxo-20-(3,5-dimethyl-1-piperidinyl)desmycosin

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100 MG
$121.00

$121.00

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100 MG
$121.00

About This Item

Empirical Formula (Hill Notation):
C46H80N2O13
Molecular Weight:
869.13
MDL number:
MFCD19705582
UNSPSC Code:
41116107
PubChem Substance ID:
329754677
NACRES:
NA.24

$121.00

Available to ship onMay 01, 2025Details

Request a Bulk Order

grade

analytical standard

Quality Level

100

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

CC1OC(OCC(C(CC)O2)/C=C(/C=C/C(C(C)CC(CCN3CC(C)CC(C)C3)C(OC4OC(C)C(O)C(N(C)C)C4O)C(C)C(O)CC2=O)=O)C)C(OC)C(OC)C1O

InChI

1S/C46H80N2O13/c1-13-36-33(24-57-46-44(56-12)43(55-11)40(53)31(8)59-46)19-25(2)14-15-34(49)28(5)20-32(16-17-48-22-26(3)18-27(4)23-48)42(29(6)35(50)21-37(51)60-36)61-45-41(54)38(47(9)10)39(52)30(7)58-45/h14-15,19,26-33,35-36,38-46,50,52-54H,13,16-18,20-24H2,1-12H3/b15-14+,25-19+/t26-,27+,28-,29+,30-,31-,32+,33-,35-,36-,38+,39-,40-,41-,42-,43-,44-,45+,46-/m1/s1

InChI key

JTSDBFGMPLKDCD-XVFHVFLVSA-N

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General description

Tilmicosin is a semisynthetic macrolide antibiotic, with broad spectrum activity towards Mycoplasma spp., Pasteurella spp., and various gram-positive organisms in animals.[1][2]

Application

Commission Regulation (EU) No 37/2010 of 22 December 2009 on pharmacologically active substances and their classification regarding maximum residue limits in foodstuffs of animal origin
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Tilmicosin may be used as a reference standard for the determination of the analyte in chicken,[2] swine,[2] cattle,[2][3] sheep tissues[2] and milk samples[3] using liquid chromatography with ultraviolet detection (LC-UV).

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - STOT RE 2

target_organs

Cardio-vascular system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
BCCM4665
BCCG2736
BCCD7299
BCCB4507
BCBV4513

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Yaqiu Zheng et al.
Analytica chimica acta, 690(2), 269-274 (2011-03-26)
A simple, sensitive and reproducible molecularly imprinted solid-phase extraction (MISPE) coupled with high performance liquid chromatographic method was developed for monitoring tilmicosin in feeds. The polymers were prepared using tylosin as mimic template molecule, methacrylic acid as functional monomer and
X F Wang et al.
Veterinary journal (London, England : 1997), 191(1), 115-120 (2011-09-09)
This study aimed to enhance the antibacterial activity of tilmicosin by solid lipid nanoparticles (SLN). Tilmicosin-loaded hydrogenated castor oil (HCO)-SLN was prepared using a hot homogenisation and ultrasonication method. The physicochemical characteristics of SLN were investigated by scanning electron microscopy
Meirong Song et al.
Drug development and industrial pharmacy, 37(6), 714-718 (2011-01-06)
The aim of this study was to use silica nanoparticles as the carrier for controlled release of tilmicosin. Tilmicosin was selected as a drug model molecule because it has a lengthy elimination half-life and a high concentration in milk after
K R Lombardi et al.
Journal of veterinary pharmacology and therapeutics, 34(6), 583-587 (2011-02-18)
The intravenous pharmacokinetic profile of tilmicosin is yet to be achieved because of the cardiovascular effects of tilmicosin. This study summarizes two pharmacokinetic studies that provided complete pharmacokinetic profile of tilmicosin in cattle. The first study was a pharmacokinetic study
P Bosi et al.
Journal of animal science, 89(12), 4043-4053 (2011-07-05)
The aim of this study was to determine the effects of 3 antibiotics used for pulmonary pathologies added in the feed of weaned pigs on growth performance, commensal microbiota, and immune response. At weaning, a total of 72 pigs were
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