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33368

Supelco

Methylmercury(II) chloride

PESTANAL®, analytical standard

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About This Item

Linear Formula:
CH3HgCl
CAS Number:
115-09-3
Molecular Weight:
251.08
Beilstein/REAXYS Number:
3600218
EC Number:
204-064-2
MDL number:
MFCD00013592
UNSPSC Code:
41116107
PubChem Substance ID:
329754499
NACRES:
NA.24

grade

analytical standard

product line

PESTANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
NMR: suitable
gas chromatography (GC): suitable

mp

170-173 °C (lit.)
170-173 °C

suitability

passes test for identity (NMR)

application(s)

agriculture
environmental

format

neat

SMILES string

C[Hg]Cl

InChI

1S/CH3.ClH.Hg/h1H3;1H;/q;;+1/p-1

InChI key

BABMCXWQNSQAOC-UHFFFAOYSA-M

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Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

PESTANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

signalword

Danger

Hazard Classifications

Acute Tox. 2 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 2 - Lact. - Repr. 1A - STOT RE 1

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

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Certificates of Analysis (COA)

Lot/Batch Number
BCCK0679
BCCF0937
BCCC6627
BCCB9586
BCCB6753

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David C Bellinger
Neurotoxicology, 33(4), 641-643 (2012-04-25)
To estimate the population burden of an exposure that is associated with neurodevelopmental impairment, it is necessary to consider both the effect size associated with the exposure (i.e., the decrease in function per unit increase in biomarker level) and the
K Vojnits et al.
Current medicinal chemistry, 19(36), 6224-6232 (2012-12-19)
Traditional approaches in evaluating the hazard of drug candidates on the developing offspring are often time-consuming and cost-intensive. Moreover, variations in the toxicological response of different animal species to the tested substance cause severe problems when extrapolating safety dosages for
Stephanie L Ondovcik et al.
Toxicology and applied pharmacology, 271(1), 41-48 (2013-04-24)
Exposure to methylmercury (MeHg) acutely at high levels, or via chronic low-level dietary exposure from daily fish consumption, can lead to adverse neurological effects in both the adult and developing conceptus. To determine the impact of variable DNA repair capacity
Shubhankar Das et al.
Chemico-biological interactions, 193(2), 129-140 (2011-06-28)
Mangiferin (MGN), a C-glucosylxanthone was investigated for its ability to protect against methylmercury (MeHg) induced neurotoxicity by employing IMR-32 (human neuroblastoma) cell line. MTT [3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide] and clonogenic cell survival assays confirmed the efficacy of MGN supplementation in attenuating MeHg-induced
Bin Xu et al.
Journal of molecular neuroscience : MN, 49(1), 162-171 (2012-12-04)
Overexposure to methylmercury (MeHg) has been known to induce neurotoxicity. The objective of this study is to explore mechanisms that contribute to MeHg-induced nerve cell apoptosis focusing on the alteration of intracellular Ca(2+) homeostasis and expression of N-methyl-D-aspartate receptors (NMDARs)
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