301310
2-Ethyl-2-thiopseudourea hydrobromide
98%
Synonym(s):
S-Ethylisothiourea hydrobromide
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All Photos(3)
About This Item
Linear Formula:
C2H5SC(=NH)NH2 · HBr
CAS Number:
Molecular Weight:
185.09
MDL number:
UNSPSC Code:
12171500
PubChem Substance ID:
Recommended Products
assay
98%
form
powder or crystals
mp
88-90 °C (lit.)
application(s)
diagnostic assay manufacturing
hematology
histology
storage temp.
room temp
SMILES string
Br.CCSC(N)=N
InChI
1S/C3H8N2S.BrH/c1-2-6-3(4)5;/h2H2,1H3,(H3,4,5);1H
InChI key
SWXXKWPYNMZFTE-UHFFFAOYSA-N
Application
Reagent used in the synthesis of pyrimidines.
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Barbara T Alexander et al.
Hypertension (Dallas, Tex. : 1979), 39(2 Pt 2), 586-590 (2002-03-08)
Acute, nonselective nitric oxide synthase inhibition in the pregnant rat decreases glomerular filtration rate and renal plasma flow, suggesting a role for nitric oxide in mediating renal vasodilation during pregnancy. As mid-gestation in the rat is associated with a significant
Claus Martin et al.
Cardiovascular research, 74(1), 46-55 (2007-01-30)
Nitric oxide (NO) synthesis by NO synthases (NOS) requires oxygen. However, although counterintuitive, NO synthesis is increased in ischemic myocardium. Accordingly, mechanisms independent of the NOS pathway have been suggested to contribute to NO synthesis during ischemia. NO initiates detrimental
A L Bardell et al.
The Journal of pharmacology and experimental therapeutics, 296(2), 252-259 (2001-02-13)
Experiments were performed to investigate whether nitric-oxide synthase (NOS) activity can be detected in vascular smooth muscle (VSM) from 12- to 14-week streptozotocin (STZ)-diabetic rats. Concentration-response curves to norepinephrine (NE) of superior mesenteric arteries from diabetic and age- and gender-matched
E Alhan et al.
The European journal of surgery = Acta chirurgica, 164(9), 697-702 (1998-09-05)
To investigate the effects of the constitutive nitric oxide (NO) synthase inhibitor NG-nitro-L-arginine methyl ester (L-Name) and the inducible NO synthase inhibitor amino ethyl-isothiourea (AE-ITU) on acute necrotising pancreatitis (ANP) in rats. Laboratory study. Medical school, Turkey. Morbidity, mortality, effects
Mihoko N Nakashima et al.
Journal of pharmacological sciences, 91(1), 47-52 (2003-04-11)
The possible role of nitric oxide (NO) in anxiety following transient cerebral ischemia by a 10-min bilateral carotid occlusion was examined in mice. Two days after the ischemia, mice showed a significant decrease in time spent on the open arms
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