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Millipore

MUG Supplement

suitable for microbiology

Synonym(s):

4-Methylumbelliferyl-β-D-glucuronide, 4-Methylumbelliferyl-β-D-glucuronide Supplement, MUGlcU

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About This Item

Empirical Formula (Hill Notation):
C16H16O9
CAS Number:
6160-80-1
Molecular Weight:
352.29
EC Number:
228-186-0
MDL number:
MFCD00036772
UNSPSC Code:
41171614
PubChem Substance ID:
329751679
NACRES:
NA.85

sterility

sterile

Quality Level

100

form

powder

shelf life

limited shelf life, expiry date on the label

application(s)

agriculture
environmental
food and beverages
microbiology

storage temp.

2-8°C

suitability

Escherichia coli
coliforms

SMILES string

O[C@@H]1[C@@H](O)[C@H](O)[C@@H](C(O)=O)O[C@H]1OC2=CC(OC(C=C3C)=O)=C3C=C2

InChI

1S/C16H16O9/c1-6-4-10(17)24-9-5-7(2-3-8(6)9)23-16-13(20)11(18)12(19)14(25-16)15(21)22/h2-5,11-14,16,18-20H,1H3,(H,21,22)/t11-,12-,13+,14-,16+/m0/s1

InChI key

ARQXEQLMMNGFDU-JHZZJYKESA-N

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Application

Fluorogenic substrate for measuring of ß-glucoronidiase activity, for identifiacation of Escherichia coli.

Components

(per vial, sufficient for 500 ml medium)
4-Methylumbelliferyl ß-D-glucuronide (MUG) 50.0 mg

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
BCCH4341
BCCG4785
BCCD8551
BCCC7285
BCCC1629

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Adrian Unc et al.
Applied and environmental microbiology, 72(3), 2287-2289 (2006-03-07)
Laboratory batch tests indicate that addition of sterile municipal sewage biosolids to clay soil from four depths increases the numbers of Escherichia coli isolates recoverable in EC-MUG broth (EC broth with 4-methylumbelliferyl-beta-glucuronide). This effect was most marked for the deeper
M Grube et al.
Naunyn-Schmiedeberg's archives of pharmacology, 368(6), 463-469 (2003-11-18)
A promising development in tumor therapy is the application of non-toxic prodrugs from which the active cytostatic is released by endogenous enzymes such as beta-glucuronidase (beta-gluc). Regulation of beta-gluc expression is one crucial factor modulating bioactivation of prodrugs. Recent experiments
Si-Cheng Liang et al.
Journal of pharmaceutical and biomedical analysis, 54(1), 236-241 (2010-09-11)
Propofol O-glucuronidation has been used as probe reaction to phenotype UGT1A9 activity in human liver, thus a sensitive and specific method for determination of propofol O-glucuronide (PG) is urgently desirable. In the current study, a new LC-ESI-MS method for determination
Mizuki Ninomiya et al.
Drug metabolism and disposition: the biological fate of chemicals, 33(2), 225-232 (2004-10-28)
We investigated whether the species difference in the biliary excretion activity of some Mrp2 substrates was attributable to the intrinsic transport potential or the expression level of Mrp2, especially in rat and dog. Dog Mrp2 cDNA was isolated from beagle
Helmut Kallwass et al.
Molecular genetics and metabolism, 90(4), 449-452 (2007-02-03)
The enzymatic defect in Pompe disease is insufficient lysosomal acid alpha-glucosidase (GAA) activity which leads to lysosomal glycogen accumulation. We recently introduced a simple and reliable method to measure GAA activity in dried blood spots using Acarbose, a highly selective
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