16583

2-Mercaptopropionic acid

analytical standard

• Synonym(s): Thiolactic acid, 2-Mercaptopropionic acid
• Linear Formula: CH₃CH(SH)COOH
• CAS Number: 79-42-5
• Molecular Weight: 106.14
• Beilstein/REAXYS Number: 506218
• EC Number: 201-206-5
• MDL number: MFCD00004862
• UNSPSC Code: 85151701
• PubChem Substance ID: 329751270
• NACRES: NA.24

Properties

• grade: analytical standard
• Quality Level: 100
• assay: ≥97.0% (GC)
• shelf life: limited shelf life, expiry date on the label
• impurities: ≤3.0% water (calc. from elemental analysis)
• refractive index: n20/D 1.481 (lit.)
• bp: 102 °C/16 mmHg (lit.); 203-208 °C (lit.)
• mp: 10-14 °C (lit.)
• density: 1.196 g/mL at 25 °C (lit.)
• application(s): cleaning products; cosmetics; food and beverages; personal care
• format: neat
• SMILES string: CC(S)C(O)=O
• InChI: 1S/C3H6O2S/c1-2(6)3(4)5/h2,6H,1H3,(H,4,5)
• InChI key: PMNLUUOXGOOLSP-UHFFFAOYSA-N

Description

General description

2-Mercaptopropionic acid is a primary metabolite of tiopronin, a drug prescribed for the treatment of cystinuria and, rheumatoid arthritis.[1]

application

2-Mercaptopropionic acid may be used as an analytical standard for the quantification of the analyte in biological fluids[1][2][3] by chromatography techniques. It may also be used as an internal standard for the thiol drug derivatization before high-performance liquid chromatography (HPLC) determination in pharmaceutical formulations by HPLC.[4]

Safety Information

• pictograms: GHS05
• signalword: Danger
• hcodes: H314
• pcodes: P260 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Skin Corr. 1B
• Storage Class: 6.1B - Non-combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• wgk_germany: WGK 1
• flash_point_f: 190.4 °F - closed cup
• flash_point_c: 88 °C - closed cup