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14405

Sigma-Aldrich

(+)-Biotin N-hydroxysuccinimide ester

≥95% (HPLC)

Synonym(s):

(+)-Biotin N-succinimidyl ester, d-Biotin NHS ester, BNHS, Biotinyl-N-hydroxy-succinimide, N-Hydroxysuccinimidobiotin, N-Succinimidyl D-biotinate, NHS-Biotin

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About This Item

Empirical Formula (Hill Notation):
C14H19N3O5S
CAS Number:
35013-72-0
Molecular Weight:
341.38
Beilstein/REAXYS Number:
4720781
MDL number:
MFCD00078531
UNSPSC Code:
12352200
PubChem Substance ID:
329750289

biological source

synthetic

Quality Level

500

assay

≥95% (HPLC)

form

powder

optical activity

[α]20/D +53±1°, c = 1% in DMF

color

white to off-white

mp

212-214 °C

storage temp.

−20°C

SMILES string

[H][C@]12CS[C@@H](CCCCC(=O)ON3C(=O)CCC3=O)[C@@]1([H])NC(=O)N2

InChI

1S/C14H19N3O5S/c18-10-5-6-11(19)17(10)22-12(20)4-2-1-3-9-13-8(7-23-9)15-14(21)16-13/h8-9,13H,1-7H2,(H2,15,16,21)/t8-,9-,13-/m0/s1

InChI key

YMXHPSHLTSZXKH-RVBZMBCESA-N

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Other Notes

Activated biotin, generally used for attaching biotin to amino acids, peptides and proteins[1]; Review: The use of the avidin-biotin complex as a tool in molecular biology[2]; On-resin biotinylation of chemically synthesized proteins for one-step purification[3]

Storage Class

13 - Non Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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