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08485

Supelco

Methoxyacetic acid

analytical standard

Synonym(s):

NSC 7300

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About This Item

Linear Formula:
CH3OCH2COOH
CAS Number:
625-45-6
Molecular Weight:
90.08
Beilstein/REAXYS Number:
635800
EC Number:
210-894-6
MDL number:
MFCD00004308
UNSPSC Code:
12352200
PubChem Substance ID:
329748590
NACRES:
NA.24

grade

analytical standard

Quality Level

100

assay

≥96.5% (GC)

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

refractive index

n20/D 1.417 (lit.)

bp

202-204 °C (lit.)

mp

7-9 °C (lit.)

density

1.174 g/mL at 25 °C (lit.)

application(s)

environmental

format

neat

SMILES string

COCC(O)=O

InChI

1S/C3H6O3/c1-6-2-3(4)5/h2H2,1H3,(H,4,5)

Inchi Key

RMIODHQZRUFFFF-UHFFFAOYSA-N

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General description

Methoxyacetic acid, a major metabolite of ethylene glycol monomethyl ether, belongs to the class of glycol ethers, which find wide use in industrial applications involving epoxy resin coatings, paints, lacquers, etc.[1][2]

Application

Methoxyacetic acid may be used as an analytical standard for the determination of the analyte in biological samples[1][2][3][4] by various chromatography techniques.

signalword

Danger

Hazard Classifications

Acute Tox. 4 Oral - Eye Dam. 1 - Repr. 1B - Skin Corr. 1B - STOT SE 3

target_organs

Respiratory system

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk_germany

WGK 2

flash_point_f

237.2 °F - closed cup

flash_point_c

114 °C - closed cup

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Certificates of Analysis (COA)

Lot/Batch Number
BCBZ4790
BCBX0220
BCBQ9829V
BCBQ9829

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A W Smallwood et al.
Environmental health perspectives, 57, 249-253 (1984-08-01)
Glycol ethers are known to produce embryotoxic and teratogenic effects in a variety of animal species. In addition, testicular edema and tubular atrophy have been reported. The health effects of this class of compounds are not known in humans, despite
E J Moss et al.
Toxicology and applied pharmacology, 79(3), 480-489 (1985-07-01)
The role of metabolism in 2-methoxyethanol (ME)-induced testicular toxicity has been investigated with Sprague-Dawley rats. Following administration of [14C]ME (250 mg/kg, ip) to a group of animals, there was evidence of testicular damage, identified as depletion of the spermatocyte population.
D Groeseneken et al.
British journal of industrial medicine, 43(1), 62-65 (1986-01-01)
Methoxyacetic acid (MAA) and ethoxyacetic acid (EAA), the major metabolites of, respectively, ethylene glycol monomethyl ether and ethylene glycol monoethyl ether and their acetates, are determined by gas chromatography after extraction from urine and methylation using 2-furoic acid (2-FA) as
Kozo Yokota et al.
International archives of occupational and environmental health, 78(8), 650-654 (2005-07-08)
To investigate whether methoxyacetic acid (MAA) is the metabolite of ethylene glycol dimethyl ether (EGdiME) in humans and whether its metabolite in urine can be used as a biomarker for exposure to EGdiME. Workers occupationally exposed to EGdiME, as well

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