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recombinant
expressed in E. coli
storage temp.
2-8°C
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Edwin R Smith et al.
Molecular and cellular biology, 28(3), 1041-1046 (2007-11-28)
Histone H3 methylation at Lys27 (H3K27 methylation) is a hallmark of silent chromatin, while H3K4 methylation is associated with active chromatin regions. Here we report that a Drosophila JmjC family member, dUTX, specifically demethylates di- and trimethylated but not monomethylated
Magdalena E Potok et al.
Proceedings of the National Academy of Sciences of the United States of America, 119(3) (2022-01-15)
ARABIDOPSIS TRITHORAX-RELATED PROTEIN 5 (ATXR5) AND ATXR6 are required for the deposition of H3K27me1 and for maintaining genomic stability in Arabidopsis Reduction of ATXR5/6 activity results in activation of DNA damage response genes, along with tissue-specific derepression of transposable elements
G Foltz et al.
Oncogene, 28(29), 2667-2677 (2009-05-26)
Epigenetic inactivation of tumor suppressor genes is a common feature in human cancer. Promoter hypermethylation and histone deacetylation are reversible epigenetic mechanisms associated with transcriptional regulation. DNA methyltransferases (DNMT1 and DNMT3b) regulate and maintain promoter methylation and are overexpressed in
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