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03582

Sigma-Aldrich

1-(Boc-amino)cyclohexanecarboxylic acid

≥98.0% (TLC)

Synonym(s):

Boc-homocycloleucine

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About This Item

Linear Formula:
(CH3)3CO2CNHC6H10CO2H
CAS Number:
115951-16-1
Molecular Weight:
243.30
Beilstein/REAXYS Number:
4189683
MDL number:
MFCD00273427
UNSPSC Code:
12352200
PubChem Substance ID:
329747735
NACRES:
NA.22

Quality Level

100

assay

≥98.0% (TLC)

form

powder with small lumps

reaction suitability

reaction type: Boc solid-phase peptide synthesis

color

white

mp

176-178 °C (dec.)

application(s)

peptide synthesis

SMILES string

CC(C)(C)OC(=O)NC1(CCCCC1)C(O)=O

InChI

1S/C12H21NO4/c1-11(2,3)17-10(16)13-12(9(14)15)7-5-4-6-8-12/h4-8H2,1-3H3,(H,13,16)(H,14,15)

InChI key

URBHKVWOYIMKNO-UHFFFAOYSA-N

Other Notes

Synthesis of modified peptides[1][2]

Storage Class

13 - Non Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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P Furet et al.
Bioorganic & medicinal chemistry letters, 10(20), 2337-2341 (2000-10-31)
Based on X-ray crystal structure information, mono charged phosphinate isosteres of phosphotyrosine have been designed and incorporated in a short inhibitory peptide sequence of the Grb2-SH2 domain. The resulting compounds, by exploiting additional interactions, inhibit binding to the Grb2-SH2 domain
M Mazzeo et al.
Journal of peptide science : an official publication of the European Peptide Society, 1(5), 330-340 (1995-09-01)
The cyclic octapeptide cyclo[-Pro1-Pro-Phe-Phe-Ac6c-Ile-ala-Val8-] [C8-Ac6c], containing the Pro1-Pro-Phe-Phe sequence, followed by a bulky helicogenic C alpha,alpha-dialkylated glycine residue Ac6c [1-aminocyclohexane-1-carboxylic acid), and a D-Ala residue at position 7 has been synthesized. This cyclic peptide is a deletion analogue of the

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