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Key Documents

00420

Sigma-Aldrich

Ethyl acetoacetate

≥98.0% (GC)

Synonym(s):

Acetoacetic ester

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About This Item

Linear Formula:
CH3COCH2COOC2H5
CAS Number:
Molecular Weight:
130.14
Beilstein/REAXYS Number:
385838
EC Number:
MDL number:
UNSPSC Code:
12352100
eCl@ss:
39022303
PubChem Substance ID:

vapor density

4.48 (vs air)

vapor pressure

1 mmHg ( 28.5 °C)

assay

≥98.0% (GC)

autoignition temp.

580 °F

expl. lim.

9.5 %

refractive index

n20/D 1.419

bp

181 °C (lit.)

mp

−43 °C (lit.)

density

1.029 g/mL at 20 °C (lit.)

SMILES string

CCOC(=O)CC(C)=O

InChI

1S/C6H10O3/c1-3-9-6(8)4-5(2)7/h3-4H2,1-2H3

InChI key

XYIBRDXRRQCHLP-UHFFFAOYSA-N

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Storage Class

10 - Combustible liquids

wgk_germany

WGK 1

flash_point_f

164.3 °F - closed cup

flash_point_c

73.5 °C - closed cup

ppe

Eyeshields, Gloves, type ABEK (EN14387) respirator filter


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Ying-Hui Sun et al.
Journal of biochemical and biophysical methods, 70(6), 850-856 (2008-01-19)
Bacterial beta-ketoacyl-ACP reductase (FabG) and the beta-ketoacyl reductase domain in mammalian fatty acid synthase (FAS) have the same function and both are rendered as the novel targets for drugs. Herein we developed a convenient method, using an available compound ethyl
Genomes as resources for biocatalysis.
Jon D Stewart
Advances in applied microbiology, 59, 31-52 (2006-07-11)
Xiao-Ting Wang et al.
Journal of biotechnology, 163(3), 292-300 (2012-11-13)
The biocatalytic anti-Prelog stereoselective reduction of ethyl acetoacetate (EAA) to ethyl (R)-3-hydroxybutyrate {(R)-EHB} was successfully conducted in the aqueous system using immobilized Acetobacter sp. CCTCC M209061 cells. Among various microorganisms tested, Acetobacter sp. CCTCC M209061 gave the best performance and
Ramakrishnan Ganesan et al.
Langmuir : the ACS journal of surfaces and colloids, 25(16), 8888-8893 (2009-09-02)
A diazoketo-functionalized alkoxysilane compound was synthesized, and its self-assembled monolayer (SAM) formation was studied on glass and silicon substrates. Infrared spectroscopy was employed to follow the photoreaction in this system, which proved that carboxylic groups were generated from diazoketo groups
Gérard Coureaud et al.
Current biology : CB, 16(19), 1956-1961 (2006-10-10)
Mammalian neonates depend on their mother's food supply and use a defined sequence of actions to find her mammary area. Their behavior is initially uncertain and demanding but rapidly becomes optimal. Efficient learning is thus operating in newborns. For instance

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