OP181

Anti-ΔNp73 Mouse mAb (38C674)

liquid, clone 38C674, Calbiochem^®

• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• biological source: mouse
• Quality Level: 100
• antibody form: purified antibody
• antibody product type: primary antibodies
• clone: 38C674, monoclonal
• form: liquid
• contains: ≤0.1% sodium azide as preservative
• species reactivity: human
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze; avoid repeated freeze/thaw cycles
• isotype: IgG1
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... TP53(7157)

Description

General description

Purified mouse monoclonal antibody. Recognizes the ~73 kDa p73 protein lacking the N-terminal transactivation domain, ΔpNp73.

Recognizes the ~73 kDa ΔNp73 protein.

This Anti-ΔNp73 Mouse mAb (38C674) is validated for use in Immunoblotting for the detection of ΔNp73.

Immunogen

Human

a synthetic peptide (LYVGDPARHLAT) corresponding to amino acids 2-13 of human ΔNp73

Application

Immunoblotting (1 g/ml, chemiluminescence)

Packaging

Please refer to vial label for lot-specific concentration.

Warning

Toxicity: Standard Handling (A)

Physical form

In PBS, 0.2% gelatin.

Reconstitution

Following initial thaw, aliquot and freeze (-20°C).

Analysis Note

Positive Control
Cell lines transfected with ΔNp73

Other Notes

Does not cross-react with full-length p73. Antibody should be titrated for optimal results in individual systems.

Levrero, M., et al. 2000 J. Cell Sci.113, 1661.
Yang, A., et al. 2000. Nature404, 99.
Ueda, Y., et al. 1999. Oncogene18, 4993.
Kaghad, M., et al. 1997. Cell90, 809.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable