Please see the full dimensions below:
Number of wells - 96
Well shape - round
Well bottom - flat
Plate length - 127.9 mm
Plate width - 85.6 mm
Plate Height - 14.6 mm
Column offset, left edge to A1 center - 14.4 mm
Row offset, top edge to A1 center - 11.4 mm
Well spacing – 9 mm
Well diameter - 6.2 mm
Well height - 12.1 mm
MAIPN4550
Multiscreen® 96 well Plate, hydrophobic PVDF membrane
pore size 0.45 μm, non-sterile
Synonym(s):
Hydrophobic 96-Well Plate, PVDF 96-Well Plate, PVDF Membrane Plate
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$1,670.00
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About This Item
$1,670.00
Recommended Products
material
PVDF membrane (hydrophobic)
acrylic
flat bottom wells
Quality Level
description
Non-sterile, clear 96-well filter plate with 0.45 um pore size Hydrophobic PVDF membrane for Avidin-biotin Linkages, DNA-binding Proteins, Protein Binding & PAMPA. Comes in a pack of 50.
sterility
non-sterile
product line
MultiScreen®
feature
hydrophobic
lid
manufacturer/tradename
MultiScreen®
parameter
50-250 μL sample volume (per well)
technique(s)
parallel artificial membrane permeation assay (PAMPA): suitable
filtration area
0.3 cm2
plate size
96 wells
well maximum volume
300 μL
working volume
50-250 μL
matrix
Immobilon®-P
pore size
0.45 μm pore size
binding type
high binding surface
shipped in
ambient
Application
- as artificial membrane support and a receiver plate in parallel artificial membrane permeation assays (PAMPA) to determine the permeabilities of oximes[1]
- in enzyme-linked immunospot (ELISpot) assay[2]
- in keyhole limpet hemocyanin (KLH)-specific ELISPOT for the identification of antigen (Ag)-specific cells[3]
Legal Information
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Articles
This is a white paper on the Evaluation of the reproducibility of Parallel Artificial Membrane Permeation Assays (PAMPA) using MultiScreen® Filter Plates.
This is a protocol for a Membrane Integrity test for Lipid-PAMPA Artificial Membranes
Combining solubility & PAMPA assays streamlines drug permeability testing.
Protocols
Assays that predict passive absorption of orally administered drugs have become increasingly important in the drug discovery process. As previously described by Faller and Kansy such assays provide rapid, low cost and automation friendly methods to measure a compound’s passive permeability.
Guidelines for various bioassays on the MultiScreen system, which makes it possible to carry out an assay from sample incubation to scintillation counting in a 96-well plate.
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I am looking for the geometry data of the plate. Respectively the height, width, and length of the full plate plus the the diameter and depth of one well.
1 answer-
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Could you please explain the meaning of the terms "donor," "acceptor," "receiver," and "collection" in relation to MAIPN4550 and MAIPN4510 filter plates?
1 answer-
The donor plate is also known as the filter plate, while the acceptor plate can be referred to as the acceptor, receiver, or collection plate. For detailed information on the PAMPA assay, you can refer to the provided link. Additionally, a datasheet is available that reviews some of the donor and acceptor plates. The donor plates include MAIPN4550 and MAIPNTR10. An alternative donor plate option is S2EM004M99, which is a 'MA' classic designed plate. It is important to note that any plate starting with 'MS---' in the catalog number cannot be used.
As for the acceptor plates, several options are available, such as MSSACCEPT0R, MATRNPS50, and MSCPNUV40.
Moreover, tech notes for the automation of PAMPA-Lipid on the Sciclone ALH 3000 workstation and the automation of PAMPA-HDM using a MultiScreen® Filter Plate on a Beckman Biomek® FX Workstation are also available. An article titled "Evaluation of the reproducibility of Parallel Artificial Membrane Permeation Assays (PAMPA)" provides further insights into the topic.
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