MABT176
Anti-SOX-6, clone 3F4.1 Antibody
clone 3F4.1, from mouse
Synonym(s):
Transcription factor SOX-6
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About This Item
UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
biological source
mouse
antibody form
purified antibody
antibody product type
primary antibodies
clone
3F4.1, monoclonal
species reactivity
human
technique(s)
western blot: suitable
isotype
IgG1κ
NCBI accession no.
UniProt accession no.
shipped in
wet ice
Gene Information
human ... SOX6(55553)
General description
The protein SOX-6 which is encoded by the gene SOX6, is a transcriptional activator that binds to the enhancer sequence in DNA of 5′AACAAT3′ that is present on genes. SOX-6 plays a key role in development for several developmental systems including neurogenesis and skeleton formation. Additionally, SOX-6 is important in cardiocyte differentiation, cartilage development, cell morphogenesis, erythrocyte development, oligodendrocyte cell fate specification, positive regulation of cartilage development, positive regulation of chondrocyte differentiation, and positive regulation of mesenchymal stem cell differentiation. The activity of SOX-6 is mediated by sumoylation. SOX-6 is localized to the nucleus. SOX-6 is expressed in a wide variety of tissues both during development and in adult life, with the most abundant expression seen in skeletal muscle.
Immunogen
GST-tagged recombinant protein corresponding to human SOX-6.
Application
Detect SOX-6 using this Anti-SOX-6 antibody, clone 3F4.1 validated for use in western blotting.
Research Category
Cell Structure
Cell Structure
Research Sub Category
Adhesion (CAMs)
Adhesion (CAMs)
Quality
Evaluated by Western Blotting in Hek-293 nuclear extract.
Western Blotting Analysis: 2.0 µg/mL of this antibody detected SOX-6 in 10 µg of Hek-293 nuclear extract.
Western Blotting Analysis: 2.0 µg/mL of this antibody detected SOX-6 in 10 µg of Hek-293 nuclear extract.
Target description
~ 92 kDa observed. Uncharacterized band(s) may appear in some lysates.
Physical form
Format: Purified
Protein G Purified
Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Storage and Stability
Stable for 1 year at 2-8°C from date of receipt.
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class
12 - Non Combustible Liquids
wgk_germany
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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