MABN514

Anti-Uncx Antibody, clone N155/9

clone N155/9, from mouse

• Synonym(s): Homeobox protein unc-4 homolog, Homeobox protein Uncx4.1
• UNSPSC Code: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Properties

• biological source: mouse
• antibody form: purified immunoglobulin
• antibody product type: primary antibodies
• clone: N155/9, monoclonal
• species reactivity: mouse
• technique(s): immunohistochemistry: suitable; western blot: suitable
• isotype: IgG1κ
• NCBI accession no.: NP_038730
• UniProt accession no.: O08934
• shipped in: wet ice
• target post-translational modification: unmodified
• Gene Information: mouse ... Uncx(22255)

Description

General description

Homeobox protein unc-4 homolog (Uncx) is also called homeobox protein Uncx4.1 and is expressed in paraxial mesoderm, the developing kidney and central nervous system. Uncx is a transcription factor involved in somitogenesis and neurogenesis. Uncx is important for the maintenance and differentiation of certain axial skeleton elements, and helps control the connections of hypothalamic neurons to pituitary elements, allowing central neurons to reach the peripheral blood circulation and to deliver hormones for control of peripheral functions.

Immunogen

Recombinant protein corresponding to mouse Uncx.

Application

Anti-Uncx Antibody, clone N155/9 is a highly specific mouse monoclonal antibody, that targets Uncx & has been tested in western blotting & IHC.

Research Category
Neuroscience

Research Sub Category
Developmental Signaling

Western Blotting Analysis: 1.0 µg/mL from a representative lot detected Uncx in 10 µg of mouse brain tissue lysate.
Immunofluorescence Analysis: A representative lot detected Uncx in mouse embryo cell lysate (Prof. J Trimmer, Univestiy of California, Davis).

Quality

Evaluated by Western Blotting in mouse E16 brain tissue lysate.

Western Blotting Analysis: 1.0 µg/mL of this antibody detected Uncx in 10 µg of mouse E16 brain tissue lysate.

Target description

~ 65 kDa observed. The calculated molecular weight of this protein is 54 kDa, but can be observed at ~65 kDa due to tissue lysates.

Physical form

Format: Purified

Protein G Purified

Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Storage and Stability

Stable for 1 year at 2-8°C from date of receipt.

Analysis Note

Control
Mouse E16 brain tissue lysate

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class: 12 - Non Combustible Liquids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable