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Key Documents

MAB5302

Sigma-Aldrich

Anti-Acetylcholine Antibody

Chemicon®, from mouse

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

mouse

Quality Level

antibody form

purified antibody

antibody product type

primary antibodies

clone

monoclonal

species reactivity

rat

manufacturer/tradename

Chemicon®

technique(s)

immunohistochemistry: suitable

isotype

IgG2a

shipped in

dry ice

Gene Information

rat ... Ache(83817)

Specificity

Acetylcholine. By immunohistochemistry on rat basal forbrain and spinal chord sections, the antibody specifically stains nerve cell bodies and fibres (Chagnaud, 1989).

The cross-reactivities were determined using an ELISA test by competition experiments with the following compounds:

Compound Cross-reactivity

Choline-GA-BSA 1

Choline-AA-BSA 1/536

Choline-SA-BSA 1/2,500

Farnesol-BSA 1/>50,000

Retinoic acid-BSA 1/>50,000

Myristic acid-BSA 1/>50,000

Acetylcholine 1/>50,000

Choline 1/>50,000

Abbreviations:

(GA) Glutaric anhydride

(AA) Adipic acid

(SA) Succinic acid

(BSA) Bovine Serum Albumin

Immunogen

Choline-Glutaric anhydride-BSA.

Application

Immunohistochemistry: 1:250-1:2,500 using free floating sections by the PAP technique on rat cholinergic areas. Tissues should be fixed with a mixture of nitrobenzyl alcohol and gluteraldehyde (Chagnaud, 1989). Gluteraldehyde is required for staining; not recommended for formalin or paraformaldehyde fixations without gluteraldehyde.

ELISA: 1:1,000-1:5,000

Immunocytochemistry: 1:1,000-1:5,000

Western Blot: 1:1,000-1:2,000

Optimal working dilutions must be determined by end user.
Research Category
Neuroscience
Research Sub Category
Neurotransmitters & Receptors
This Anti-Acetylcholine Antibody is validated for use in IH for the detection of Acetylcholine.

Physical form

Format: Purified
Liquid containing 0.05% sodium azide.

Storage and Stability

Maintain at 2-8°C in undiluted aliquots for up to 6 months after date of receipt.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

10-13 - German Storage Class 10 to 13


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Therapeutic Effect of Yi-Chi-Tsung-Ming-Tang on Amyloid ?-Induced Alzheimer's Disease-Like Phenotype via an Increase of Acetylcholine and Decrease of Amyloid ?.
Yeh, CH; Hsieh, MT; Hsueh, CM; Wu, CR; Huang, YC; Liao, JW; Chow, KC
Evidence-Based Complementary and Alternative Medicine : ECAM null

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