MAB430-I
Anti-Epithelium Endothelial Cells Antibody, clone PHM-5
clone 18.29 (PHM-5), from mouse
Synonym(s):
Glomerular endothelial cells, Glomerular epithelial cells
Sign Into View Organizational & Contract Pricing
All Photos(1)
Select a Size
Change View
25 μG
$182.00
100 μG
$498.00
About This Item
UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.43
biological source
mouse
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
18.29 (PHM-5), monoclonal
species reactivity
human
packaging
antibody small pack of 25 μg
technique(s)
immunohistochemistry: suitable (paraffin)
isotype
IgG1κ
NCBI accession no.
target post-translational modification
unmodified
Related Categories
General description
The glomeruli network of capillaries filters the blood and the filtrate then enters the renal tubule. Unlike most capillary beds, the glomerular capillaries exit into efferent arterioles rather than venules. The resistance that exists in efferent arterioles causes sufficient hydrostatic pressure within the glomerulus to provide the force for ultrafiltration. Glomerular endothelial cells that create an interface between blood and tissue compartments are responsible for regulating vasomotor tone, trafficking of leukocytes, and maintenance of maintain hemostasis. Unlike endothelium in other tissues, the normal glomerular endothelium is extremely attenuated, being only about 50 to 150 nm in height around the perimeter of the capillary loops. Glomeruli of human kidneys are shown to be rich sialoglycoprotein, which is chemically distinct from rat podocalyxin. (Ref.: Ballermann, BJ (2005). Kidney Int. 67(5); 1668-1671; Kerjaschki, D., et al. (1986). J. Clin. Invest. 78(5); 1142-1149).
Specificity
Clone PHM-5 is a mouse monoclonal antibody that detects human epithelium/endothelial cells.
Immunogen
Human Glomerular cells.
Application
Anti-Epithelium Endothelial Cells, clone PHM-5, Cat. No. MAB430-I, is a mouse monoclonal antibody that detects human human epithelium/endothelial cells and has been tested for use in Immunohistochemistry (Paraffin).
Immunohistochemistry (Paraffin) Analysis: A 1:50 dilution from a representative lot detected Epithelium Endothelial Cells in human cerebral cortex tissue sections.
Research Category
Cell Structure
Cell Structure
Quality
Evaluated by Immunohistochemistry (Paraffin) in human kidney tissue sections.
Immunohistochemistry (Paraffin) Analysis: A 1:50 dilution of this antibody detected Epithelium Endothelial Cells in human kidney tissue sections.
Immunohistochemistry (Paraffin) Analysis: A 1:50 dilution of this antibody detected Epithelium Endothelial Cells in human kidney tissue sections.
Physical form
Format: Purified
Protein G purified
Purified mouse monoclonal antibody IgG1 in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Storage and Stability
Stable for 1 year at 2-8°C from date of receipt.
Other Notes
Concentration: Please refer to lot specific datasheet.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Not finding the right product?
Try our Product Selector Tool.
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Active Filters
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service
