MAB1682
Anti-Actinin α Antibody, clone AT6/172
ascites fluid, clone AT6/172, Chemicon®
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About This Item
UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
biological source
mouse
antibody form
ascites fluid
antibody product type
primary antibodies
clone
AT6/172, monoclonal
species reactivity
human
manufacturer/tradename
Chemicon®
technique(s)
immunofluorescence: suitable
immunoprecipitation (IP): suitable
western blot: suitable
isotype
IgG1
NCBI accession no.
UniProt accession no.
shipped in
dry ice
Gene Information
human ... ACTN1(87)
Specificity
Human alpha actinin. This antibody recognizes an epitope in the N-terminal region of alpha-actinin, probably between residues 1-24.
Immunogen
Epitope: alpha
Human platelet protein
Application
Anti-Actinin Antibody, α, clone AT6/172 detects level of Actinin & has been published & validated for use in IF, IP & WB.
Immunoblotting: ~100kDa on SDS reducing gels
Immunoprecipitation
Immunofluorescence: methanol fixed cells
Immunohistochemistry
Optimal working dilutions must be determined by end user.
Immunoprecipitation
Immunofluorescence: methanol fixed cells
Immunohistochemistry
Optimal working dilutions must be determined by end user.
Research Category
Cell Structure
Cell Structure
Research Sub Category
Cytoskeleton
Cytoskeleton
Physical form
Liquid
Storage and Stability
Maintain frozen at -20°C for up to 12 months in undiluted aliquots. Avoid repeated freeze/thaw cycles.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class
10 - Combustible liquids
wgk_germany
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Lisa A McPherson et al.
DNA repair, 83, 102644-102644 (2019-07-18)
Cellular homeostasis is dependent on a balance between DNA damage and DNA repair mechanisms. Cells are constantly assaulted by both exogenous and endogenous stimuli leading to high levels of reactive oxygen species (ROS) that cause oxidation of the nucleotide dGTP
Myriam Jaraíz-Rodríguez et al.
Stem cell reports, 9(2), 451-463 (2017-07-18)
Connexin43 (CX43), a protein that forms gap junction channels and hemichannels in astrocytes, is downregulated in high-grade gliomas. Its relevance for glioma therapy has been thoroughly explored; however, its positive effects on proliferation are counterbalanced by its effects on migration
L Valmu et al.
European journal of immunology, 29(7), 2107-2118 (1999-07-31)
Leukocyte adhesion is a regulated process, which involves CD11/CD18 leukocyte integrins. CD11/CD18 acidity may be regulated intracellularly, and the CD18 polypeptide has previously been shown to become phosphorylated on serine and threonine after phorbol ester activation of T cells. Increased
Lin Ning et al.
Biology open, 4(2), 125-136 (2015-01-13)
ICAM-5 is a negative regulator of dendritic spine maturation and facilitates the formation of filopodia. Its absence results in improved memory functions, but the mechanisms have remained poorly understood. Activation of NMDA receptors induces ICAM-5 ectodomain cleavage through a matrix
Sharissa L Latham et al.
Nature communications, 9(1), 4250-4250 (2018-10-14)
Germline mutations in the ubiquitously expressed ACTB, which encodes β-cytoplasmic actin (CYA), are almost exclusively associated with Baraitser-Winter Cerebrofrontofacial syndrome (BWCFF). Here, we report six patients with previously undescribed heterozygous variants clustered in the 3'-coding region of ACTB. Patients present
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