GF032
Neurotrophin 4/5
The Neurotrophin-4 protein (or NT-4/NT-5 protein) is a potent neurotrophic factor which supports the growth & survivability of nerve and/or glial cells.
Synonym(s):
NT4/5
Sign Into View Organizational & Contract Pricing
All Photos(1)
About This Item
UNSPSC Code:
12352200
eCl@ss:
32160405
NACRES:
NA.75
biological source
human
Quality Level
assay
>98% (SDS-PAGE and HPLC)
manufacturer/tradename
Chemicon®
impurities
<0.1 ng/mg Endotoxin (of NT-4; 1EU/mg)
NCBI accession no.
UniProt accession no.
shipped in
dry ice
General description
Neurotrophin-4 (NT-4/NT-5) is a potent neurotrophic factor which supports the growth and survivability of nerve and/or glial cells. The active form of human NT-4 is a dimer, formed by two identical 130 amino acid subunits, which is held together by strong hydrophobic interactions.
Product Source: Human NT4/5 expressed in E.coli
Application
Concentration range for most in vitro applications is 0.5 to 100 ng/mL. Responding cells include (partial list): Nerve, glial cells.
Storage and Stability
The lyophilized powder, though stable at room temperature, is best stored desiccated below 0°C for up to 12 months after date of receipt. After a quick spin, reconstitute with sterile water to a concentration of 0.1-1.0 mg/mL. This solution can be diluted into other aqueous buffers. Reconstitute NT-4 should be stored in undiluted aliquots at -20°C for up to six months.
Analysis Note
Specific Activity: Chemicon′s human NT-4 is fully biologically active when compared to standards. The ED(50) as determined by the dose-dependent induction of choline acetyl transferase activity in rat basal forebrain primary septal cultures.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Storage Class
11 - Combustible Solids
wgk_germany
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Active Filters
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service
