FCMAB306P
Milli-Mark Anti-Human-Nuclei-PE Antibody, clone 235-1
clone 235-1, Milli-Mark®, from mouse
Synonym(s):
HuNu
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About This Item
UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Recommended Products
biological source
mouse
Quality Level
conjugate
PE
antibody form
purified antibody
antibody product type
primary antibodies
clone
235-1, monoclonal
species reactivity (predicted by homology)
human (based on 100% sequence homology)
manufacturer/tradename
Milli-Mark®
technique(s)
flow cytometry: suitable
isotype
IgG1κ
shipped in
wet ice
target post-translational modification
unmodified
General description
Stem-cell and fetal-cell replacement therapies for many diseases have proven to be very hopeful. Human nuclei antibodies are very important histological and cytological markers for identifying human cells. The use of human nuclei and C-peptide to force differentiation of human mesenchymal stem cells into insulin-producing cells to treat diabetes mellitus in mice has been successful. Human nuclei cells have also been associated with using stem-cell treatment in spinal cord injuries in canines.
Specificity
Stains nuclei of all human cell types giving a diffuse nuclear staining pattern. Chromosomes are negatively stained in metaphase cells. Also stains nuclei from primate (Sanchez-Pernaute, 2005). The antibody does not react with nuclei from mouse or rat.
Application
Detect Human-Nuclei using this Milli-Mark Anti-Human-Nuclei-PE Antibody, clone 235-1 validated for use in FC.
Research Category
Stem Cell Research
Stem Cell Research
Research Sub Category
Neural Stem Cells
Neural Stem Cells
Quality
Evaluated by flow cytometry using Jurkat cells.
Physical form
Protein A purified
Purified mouse monoclonal IgG1κ conjugated to PE in PBS with 0.1% sodium azide and 15 mg/mL BSA.
Storage and Stability
Maintain refrigerated at 2-8 °C protected from light in undiluted aliquots for up to 6 months from date of receipt.
Analysis Note
Control
Jurkat cells.
Jurkat cells.
Legal Information
MILLI-MARK is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class
10 - Combustible liquids
wgk_germany
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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