SAP90/PSD-95-associated protein 2 (SAPAP2, also known as DLGAP2) is a member of a protein family whose members specifically interact with PSD-95/SAP90, a membrane-associated guanylate kinase localized at postsynaptic density (PSD) in neuronal cells. Like the other SAPAP proteins, SAPAP2 is thought to be an adaptor protein that also interacts with different synaptic scaffolding proteins, cytoskeletal and signaling components, such as focal adhesion kinase (FAK) and proline-rich tyrosine kinase 2 (PYK2).
Specificity
At least three isoforms of SAPAP2 are known to exist. This SAPAP2 antibody will not cross-react with other SAPAP proteins.
Immunogen
KLH-conjugated linear peptide corresponding to human SAPAP2.
Application
Immunohistochemistry Analysis: 5 µg/mL of this antibody from a representative lot detected SAPAP2 in human brain tissue.
Research Category Neuroscience
Research Sub Category Synapse & Synaptic Biology
This SAPAP2 antibody is validated for use in WB & IHC for the detection of the SAPAP2 protein.
Quality
Evaluated by Western Blot in L1210 cell lysate.
Western Bloting Analysis: 1 µg/mL of this antibody detected SAPAP2 in 15 µg of L1210 cell lysate.
Target description
~114 kDa observed. Uncharacterized bands may be observed.
Physical form
Antigen Affinity Purified
Purified rabbit polyclonal in buffer containing PBS and 0.02% sodium azide.
Storage and Stability
Stable for 1 year at 2-8°C from date of receipt.
Analysis Note
Control L1210 cell lysate
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class
12 - Non Combustible Liquids
wgk_germany
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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