ABN345

Anti-Slitrk2 Antibody

from rabbit

• Synonym(s): SLIT and NTRK-like protein 2, CXorf2, SLITL1, KIAA1854, slit-like 1, SLIT and NTRK-like protein 2, slit and trk like gene 2
• UNSPSC Code: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Properties

• biological source: rabbit
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• species reactivity: human, rat
• technique(s): immunohistochemistry: suitable; western blot: suitable
• UniProt accession no.: Q9H156
• shipped in: wet ice
• target post-translational modification: unmodified
• Gene Information: human ... SLITRK2(84631)

Description

General description

SLIT and NTRK-like family 2 (Slitrk2) is a member a protein family consisting of six homologous transmembrane proteins (Slitrk1-6) that share two conserved leucine-rich repeat domains in the extracellular domain and have significant homology to Slit, a secreted axonal growth-controlling protein. These proteins are also homologous to trk neurotrophin receptors in their intracellular domains. Expression of Slitrk proteins is highly restricted to neural and brain tumor tissues, but varies within the family. For example, Slitrk2 is expressed primarily in neurons in the ventricular layer of the brain. Like every other Slitrk protein except Slitrk1, overexpression of Slitrk2 inhibited neurite outgrowth in cultured neurons. At least two isoforms of this protein are known to exist.

Immunogen

KLH-conjugated linear peptide corresponding to human Slitrk2.

Application

Immunohistochemistry Analysis: 2.5 µg/mL from a representative lot detected Slitrk2 in human brain tissue.

Research Category
Neuroscience

Neuroscience

Research Sub Category
Developmental Neuroscience

Neurofilament & Neuron Metabolism

This Slitrk2 antibody is validated for use in WB & IHC for the detection of the Slitrk2 protein.

Quality

Evaluated by Western Blot in rat brain tissue lysate.

Western Blot Analysis: 2 µg/mL of this antibody detected Slitrk2 in 15 µg of rat brain tissue lysate.

Target description

~98 kDa observed

Physical form

Antigen Affinity Purified

Format: Purified

Purified rabbit polyclonal in buffer containing PBS with 0.02% sodium azide.

Storage and Stability

Stable for 1 year at 2-8°C from date of receipt.

Analysis Note

Control
Rat brain tissue lysate

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class: 12 - Non Combustible Liquids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable