ABN213

Anti-IL-12 alpha Antibody

from rabbit, purified by affinity chromatography

• Synonym(s): Interleukin-12 subunit alpha, IL-12A, Cytotoxic lymphocyte maturation factor 35 kDa subunit, CLMF p35, IL-12 subunit p35, NK cell stimulatory factor chain 1, NKSF1
• UNSPSC Code: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Properties

• biological source: rabbit
• Quality Level: 100
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• purified by: affinity chromatography
• species reactivity: human
• technique(s): immunohistochemistry: suitable (paraffin); western blot: suitable
• NCBI accession no.: NP_000873
• UniProt accession no.: P29459
• shipped in: wet ice
• target post-translational modification: unmodified
• Gene Information: human ... IL12A(3592)

Description

General description

Interleukin-12 alpha (IL-12A) is also known as Cytotoxic lymphocyte maturation factor 35 kDa subunit (CLMF p35), IL-12 subunit p35, or NK cell stimulatory factor chain 1 (NKSF-1). IL-12A is a cytokine that, along with IL12B, forms a disulfide-linked heterodimer interleukin IL-12. IL-12 alpha functions as a regulator of T cell mediated cytotoxicity, interferon-gamma production, lymphocyte proliferation and activation of natural killer cells.

Specificity

This antibody recognizes the near C-terminus of IL-12 alpha

Immunogen

KLH-conjugated linear peptide corresponding to the near C-terminus of human IL-12 alpha.

Application

Immunohistochemistry Analysis: A 1:16,000-32,000 dilution from a representative lot detected IL-12 alpha in human tonsil and human brain tissue.

This IL-12 alpha antibody is validated for use in WB & IHC for the detection of the IL-12 alpha protein.

Quality

Evaluated by Western Blotting in human lymph node tissue lysate.

Western Blotting Analysis: 0.2 µg/mL of this antibody detected IL-12 alpha in 10 µg of human lymph node tissue lysate.

Target description

~25 kDa observed

Linkage

Replaces: MABN1084

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Safety Information

• Storage Class: 12 - Non Combustible Liquids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable