ABF211

Anti-Tirap Antibody

from rabbit, purified by affinity chromatography

• Synonym(s): Toll/interleukin-1 receptor domain-containing adapter protein, TIR domain-containing adapter protein, Adaptor protein Wyatt, MyD88 adapter-like protein
• UNSPSC Code: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Properties

• biological source: rabbit
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• purified by: affinity chromatography
• species reactivity: human
• species reactivity (predicted by homology): mouse (immunogen homology)
• technique(s): immunofluorescence: suitable; immunohistochemistry: suitable; western blot: suitable
• UniProt accession no.: Q99JY1
• shipped in: wet ice
• target post-translational modification: unmodified
• Gene Information: human ... TIRAP(114609)

Description

General description

Toll/interleukin-1 receptor domain-containing adapter protein (Tirap), also known as MyD88 adapter-like protein (Mal), contains one TIR domain that is involved in the TLR2 and TLR4 signaling pathways in the innate immune response. Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection serving as an important link between the innate and adaptive immune responses.

Specificity

This antibody recognizes the C-terminus of Tirap.

Immunogen

Epitope: C-terminus

KLH-conjugated linear peptide corresponding to the C-terminus of mouse Tirap.

Application

Detect Toll/interleukin-1 receptor domain-containing adapter protein using this rabbit polyclonal antibody, Anti-Tirap Antibody validated for use in western blotting, IHC & Immunofluorescence.

Immunohistochemistry Analysis: 2 µg/mL from a representative lot detected Tirap in human heart tissue.

Immunofluorescence Analysis: 10 µg/mL from a representative lot detected Tirap in human heart tissue.

Research Category
Inflammation & Immunology

Research Sub Category
Immunoglobulins & Immunology

Quality

Evaluated by Western Blotting in human heart tissue lysate.

Western Blotting Analysis: 2 µg/mL of this antibody detected Tirap in 15 µg of human heart tissue lysate.

Target description

~35 kDa observed

Physical form

Antigen Affinity Purified

Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.

Storage and Stability

Stable for 1 year at 2-8°C from date of receipt.

Analysis Note

Control
Human heart tissue lysate

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class: 12 - Non Combustible Liquids
• wgk_germany: WGK 2
• flash_point_f: Not applicable
• flash_point_c: Not applicable