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Key Documents

AB9634

Sigma-Aldrich

Anti-DLG4 Antibody

CHEMICON®, rabbit polyclonal

Synonym(s):

PSD-95

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

Product Name

Anti-Post Synaptic Density 95 Antibody, Chemicon®, from rabbit

biological source

rabbit

antibody form

affinity purified immunoglobulin

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

rat

manufacturer/tradename

Chemicon®

technique(s)

western blot: suitable

isotype

IgG

NCBI accession no.

UniProt accession no.

shipped in

dry ice

target post-translational modification

unmodified

Gene Information

rat ... Dlg4(29495)

Specificity

Postsynaptic density 95 (PSD-95). The antibody recognizes a protein of ~95 kDa corresponding to PSD-95 in lysates from rat brain hippocampus. An additional band of ~44 kDa may also be seen depending on sample and antibody concentration used.
The immunogen has 100% similarity with human and mouse.

Immunogen

Synthetic peptide from the N-terminal of rat PSD-95.

Application

Research Category
Neuroscience
Research Sub Category
Synapse & Synaptic Biology
This Anti-Post Synaptic Density 95 Antibody is validated for use in WB for the detection of Post Synaptic Density 95.
Western blot: 1:1,000

Optimal working dilutions must be determined by the end user.

Linkage

Replaces: 04-1066

Physical form

Affinity purified immunoglobulin. Liquid in 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50% glycerol.

Storage and Stability

Maintain at -20°C in undiluted for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles. Do not store in a self defrosting freezer.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

10 - Combustible liquids

wgk_germany

WGK 2


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Sung Woo Park et al.
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Mood-stabilizing drugs, such as lithium (Li) and valproate (VPA), are widely used for the treatment of bipolar disorder, a disease marked by recurrent episodes of mania and depression. Growing evidence suggests that Li exerts neurotrophic and neuroprotective effects, leading to
Kathryn J Reissner et al.
Journal of neurochemistry, 105(3), 1006-1018 (2008-01-10)
The vertebrate post-synaptic density (PSD) is a region of high molecular complexity in which dynamic protein interactions modulate receptor localization and synaptic function. Members of the membrane-associated guanylate kinase (MAGUK) family of proteins represent a major structural and functional component
Sung Woo Park et al.
Synapse (New York, N.Y.), 67(5), 224-234 (2013-01-22)
Recent evidence has suggested that atypical antipsychotic drugs regulate synaptic plasticity. We investigated whether some atypical antipsychotic drugs (olanzapine, aripiprazole, quetiapine, and ziprasidone) altered the expression of synapse-associated proteins in rat hippocampal neuronal cultures under toxic conditions induced by B27
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Qian Ge et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 35(4), e21244-e21244 (2021-03-15)
Excess salt intake harms the brain health and cognitive functions, but whether a maternal high-salt diet (HSD) affects the brain development and neural plasticity of offspring remains unclear. Here, using a range of behavioral tests, we reported that the offspring

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