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AB3534P

Sigma-Aldrich

Anti-Epithelial Sodium Channel-γ Antibody

Chemicon®, from rabbit

Synonym(s):

ENaC-gamma

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

rabbit

Quality Level

100

antibody form

affinity purified immunoglobulin

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

rat, mouse

manufacturer/tradename

Chemicon®

technique(s)

ELISA: suitable
western blot: suitable

NCBI accession no.

NM_001039.3

UniProt accession no.

P51170

shipped in

dry ice

target post-translational modification

unmodified

Gene Information

human ... SCNN1G(6340)

Specificity

Recognizes rat Epithelial Sodium Channel gamma (ENaC gamma). The immunogen shows no significant sequence homology with other ENaC subunits.

SPECIES REACTIVITIES: The immunogen sequence is 100% conserved in mouse, 92% in human, 80% in rabbit. Reactivity with other species has not been confirmed.

Immunogen

A 14 amino acid peptide sequence near the N-terminus of rat ENaC gamma (Linguela et al. 1993; Canessa et al.

1993; Snyder et al. 1994; Waldmann et al. 1995; Kreutz et al. 1997; Voilley et al.

1994; McDonald et al. 1994; Ludwig et al. 1998; Garty & Palmer 1997).

Application

Detect Epithelial Sodium Channel-γ using this Anti-Epithelial Sodium Channel-γ Antibody validated for use in ELISA & WB.
Western blot: 1-10 μg/mL using ECL. 83-90kDa bands; Masilamani et al 1999

ELISA: 1:10,000-1:100,000 using 1 mg/mL control peptide coated on well.

Optimal working dilutions must be determined by the end user.

Physical form

Affinity purified immunoglobulin. Liquid in PBS, containing 0.1% BSA.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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Storage Class

12 - Non Combustible Liquids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Takahiro Masuda et al.
American journal of physiology. Renal physiology, 315(3), F653-F664 (2018-05-24)
The chronic intrinsic diuretic and natriuretic tone of sodium-glucose cotransporter 2 (SGLT2) inhibitors is incompletely understood because their effect on body fluid volume (BFV) has not been fully evaluated and because they often increase food and fluid intake at the

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