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AB1967

Sigma-Aldrich

Anti-Integrin αIIb Antibody, cytoplasmic domain

serum, Chemicon®

Synonym(s):

Glycoprotein IIb, CD41 Antigen

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

rabbit

Quality Level

100

antibody form

serum

antibody product type

primary antibodies

clone

polyclonal

species reactivity

human

manufacturer/tradename

Chemicon®

technique(s)

ELISA: suitable
immunoprecipitation (IP): suitable

NCBI accession no.

NM_000419.3

UniProt accession no.

P08514

shipped in

dry ice

target post-translational modification

unmodified

Gene Information

human ... ITGA2B(3674)

Specificity

Human integrin alpha Iib

Immunogen

Epitope: cytoplasmic domain
Synthetic peptide corresponding to the cytoplasmic domain of human integrin alphaIIb

conjugated to KLH. (a.a. 1020-1039, KVGFFKRNRPPLEEDDEEGE)

Application

Anti-Integrin αIIb Antibody, cytoplasmic domain is an antibody against Integrin αIIb for use in ELISA & IP.
Immunoprecipitation

ELISA: Direct 1:500 with 5% milk in PBS or TBS at pH 7.4

Optimal working dilutions must be determined by the end user.
Research Category
Cell Structure
Research Sub Category
Integrins

Physical form

Whole rabbit serum. Liquid containing no preservative.

Storage and Stability

Maintain at -20ºC in undiluted aliquots for up to twelve months from date of receipt. Avoid

repeated freeze/thaw cycles.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

10 - Combustible liquids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Mareike G Posner et al.
The Journal of biological chemistry, 291(6), 2764-2776 (2015-12-03)
Extracellular fibrinogen-binding protein (Efb) from Staphylococcus aureus inhibits platelet activation, although its mechanism of action has not been established. In this study, we discovered that the N-terminal region of Efb (Efb-N) promotes platelet binding of fibrinogen and that Efb-N binding

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