Autophagy is the process by which cells recycle cytoplasm and dispose of excess or defective organelles. This process is suggested to be involved development, differentiation, growth regulation and tissue remodeling in multicellular organisms. Beclin 1 is a BCL-2 interacting protein and this protein was shown to play a role in the promotion of autophagy.
Synthetic peptide corresponding to the C-terminus of human Beclin 1 protein.
Application
Detect Beclin 1 using this Anti-Beclin 1 Antibody validated for use in WB, IC, IH.
Research Category Neuroscience
Research Sub Category Neurodegenerative Diseases
Western blot: 1:100-1:2,000 Immunocytochemistry: 1:100-1:2,000 Immunohistochemistry: 1:100-1:2,000 Optimal working dilutions must be determined by end user.
Linkage
Replaces: MABN16
Physical form
Lyophilized. Reconstitute with 50 μL of sterile distilled water. Centrifuge to remove any insoluble material. Contains no preservative.
Serum
Storage and Stability
Maintain lyophilized material frozen at -20°C to -70°C for up to 12 months after date of receipt. After reconstitution maintain at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles. Glycerol (1:1, ACS or better grade) can be added for additional stability.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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