AB15408

Anti-APG10 Antibody

serum, Chemicon^®

• Synonym(s): Autophagy-related protein 10, APG10-like, ATG10
• UNSPSC Code: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Properties

• biological source: rabbit
• antibody form: serum
• antibody product type: primary antibodies
• clone: polyclonal
• species reactivity: human
• manufacturer/tradename: Chemicon^®
• technique(s): immunocytochemistry: suitable; immunohistochemistry: suitable; western blot: suitable
• NCBI accession no.: NM_031482.3
• UniProt accession no.: Q9H0Y0
• shipped in: wet ice
• target post-translational modification: unmodified
• Gene Information: human ... ATG10(83734)

Description

General description

Autophagy is the process by which cells recycle cytoplasm and dispose of excess or defective organelles. This process is suggested to be involved development, differentiation, growth regulation and tissue remodeling in multicellular organisms. The APG10 protein plays a role in the conjugation of APG5 to APG12 and this conjugate is required for elongation of the isolation membrane to form a complete spherical autophagosome. The APG10 is able to interact with MAP1LC3A and with APG5 and APG7.

Specificity

APG10 [Autophagy-related protein 10, APG10-like, ATG10].

Immunogen

Synthetic peptide corresponding to a region within the C-terminus of human APG10 protein.

Application

Anti-APG10 Antibody detects level of APG10 & has been published & validated for use in WB, IC, IH.

Research Category
Neuroscience

Research Sub Category
Neurodegenerative Diseases

Western blot: 1:200-1:1,000
Immunocytochemistry: 1:200-1:1,000
Immunohistochemistry: 1:200-1:1,000
Optimal working dilutions must be determined by end user.

Physical form

Lyophilized. Reconstitute with 50 μL of sterile distilled water. Centrifuge to remove any insoluble material. Contains no preservative.

Serum

Storage and Stability

Maintain lyophilized material frozen at -20°C to -70°C for up to 12 months after date of receipt. After reconstitution maintain at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles. Glycerol (1:1, ACS or better grade) can be added for additional stability.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class: 10 - Combustible liquids